INTRODUCTIONThe skin barrier is a highly organized system in which structural proteins, intercellular lipids, and natural moisturizing factors (NMFs) work together to maintain moisture content, regulate desquamation, and protect against…
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INTRODUCTIONXerotic and hyperkeratotic skin conditions represent a substantial proportion of dermatologic consultations and are associated with both physical discomfort and psychosocial burden. These conditions encompass a wide spectrum of disorders,…
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In this issue: Beyond Moisturization: Ammonium Lactate as a Biomimetic Regulator of Skin Barrier Function The skin barrier is a highly organized system in which structural proteins, intercellular lipids, and…
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INTRODUCTIONAtopic dermatitis (AD) is a common inflammatory skin disease with a relapsing and remitting course over a patient's lifetime.1,2 This chronic skin condition is estimated to affect up to 20%…
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INTRODUCTIONSeborrheic dermatitis (SD) is a chronic, relapsing inflammatory condition that predominantly affects sebaceous gland-rich areas such as the scalp, face, and chest.1 Characterized by erythematous scaly patches, SD affects up…
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INTRODUCTIONMenopause is a physiological stage in a woman's life characterized by the permanent cessation of ovarian follicular activity and a consequent decline in circulating estrogen levels. This transition reflects a…
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INTRODUCTIONChronic pruritus remains one of the most challenging symptoms to manage across dermatologic and systemic conditions, significantly impairing quality of life and often proving refractory to conventional therapies. Nemolizumab represents…
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INTRODUCTIONAtopic dermatitis (AD) is a chronic inflammatory skin condition that typically begins in infancy, peaks in early childhood, and persists into adulthood.1,2 Clinical features of pediatric AD include a relapsing…
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INTRODUCTIONAtopic dermatitis (AD) is a chronic, relapsing skin disease presenting with inflammation, pruritus, and xerosis.1,2 A family history of atopy and related comorbidities such as asthma and allergic rhinitis is…
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INTRODUCTIONPigmentary disorders, including cutaneous hyperpigmentation, are among the most common dermatologic diagnoses in individuals with SOC, particularly individuals with African, Asian, or Hispanic heritage.1,2 The principal hyperpigmentation conditions include melasma,…
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INTRODUCTIONInhibition of interleukin (IL)-13, a key mediator of type 2 inflammation, is a highly effective and targeted therapeutic strategy for atopic dermatitis (AD).1 Despite an excellent safety profile, ocular adverse…
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INTRODUCTIONDermatoporosis is an age-related condition characterized by progressive loss of the skin's mechanical strength and structural integrity.1 It first presents as fragile skin with senile purpura, stellate pseudoscars, and skin…
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