Aesthetic patients are increasingly aware of the contrast between rejuvenated facial skin and untreated aging skin of the décolletage, and frequently request cosmetic enhancement of this area. Poly-L-lactic acid (Sculptra^®, Galderma; PLLA-SCA) is a regenerative biostimulator that stimulates collagen and elastin production to help regenerate the skin’s inner structure.

Acne vulgaris is a debilitating disease involving the sebaceous glands and the proliferation of Propionibacterium acnes (P. acnes). This skin condition is highly prevalent in the adolescent population, affecting over 85% of teenagers, and approximately 9.4% of the global population.^1,2 

Rosacea is a chronic inflammatory disease characterized by recurrent facial flushing, erythema, papules, and pustules. While its precise etiology remains unclear, immunological dysregulation, genetic disposition, and environmental factors have all been proposed as possible causative factors.¹ Rosacea has a global incidence of almost 10% and commonly affects women aged 35–50.² In addition to experiencing symptoms like dryness, burning, and itching on the face, 50% to 75% of patients with rosacea also have ocular involvement.¹ Due to the highly visible manifestations of rosacea, the condition has been linked to self-reported feelings of stigmatization, low self-esteem, and social anxiety.³

Atopic dermatitis (AD) is an inflammatory skin disease marked by intense pruritus, impaired skin barrier function, and recurrent flares.¹ Its prevalence in the United States is estimated to range from 8.7% to 18.1%, and an estimated 2.6% of individuals are affected by AD globally.^2,3 Disease burden can manifest in various ways, including lower quality-of-life scores, reduced sleep quality, and increased workplace absenteeism.^4,5