INTRODUCTIONExosomes are extracellular vesicles released by cells that transfer proteins, lipids, mRNAs, and microRNAs to recipient cells playing a role in intercellular communication.1 Recent studies have highlighted exosomes' role in…
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INTRODUCTIONIncreasingly, therapeutic advancements in dermatology favor targeted modalities, such as monoclonal antibodies and biologic therapies, which specifically address inflammatory cytokines, offering alternatives to broader immunosuppressive treatments.1,2 Janus kinase (JAK) inhibitors…
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INTRODUCTIONHyperpigmentation and dyschromia are amongst the most common dermatologic concerns for patients seeking care.1 They can affect patients of all skin types and ages, and most commonly occurs after inflammation…
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In this issue:INDIVIDUAL ARTICLE: Real World Use of Topical Tranexamic Acid Serum in Patients With HyperpigmentationHyperpigmentation and dyschromia are amongst the most common dermatologic concerns for patients seeking care.1 They…
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INTRODUCTIONDystrophic epidermolysis bullosa (DEB), caused by mutations in COL7A1 is characterized by the development of blisters, bullae, and erosions following minor trauma to the skin and mucous membranes, with healing…
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INTRODUCTIONThe United States Medical Licensing Examination (USMLE) will stop reporting a 3-digit numerical score and begin reporting a pass/fail outcome at the end of January 2022.1,2 The proposal for this…
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INTRODUCTIONDermatoporosis is a term first coined by Kaya and Saurat in 2007, describing progressive skin thinning, extracellular matrix (ECM) degradation, vascular fragility with resultant purpura, and general vulnerability of the…
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INTRODUCTIONHyperhidrosis (HH) is defined as excessive sweating beyond the physiologic requirements of thermoregulation.1 HH is classified as either primary (idiopathic) or secondary to an underlying medical condition or medication.1 Primary…
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INTRODUCTIONNail disorders encompass a broad spectrum of infectious, inflammatory, neoplastic, and traumatic conditions that may present with overlapping clinical features. They represent approximately 10% of all dermatologic conditions, accounting for…
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INTRODUCTIONIn recent years, there has been a notable increase in attention to and financial support for dermatology.1,2 Skin conditions now rank as the fourth leading contributor to nonfatal disease burden…
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INTRODUCTIONAcne vulgaris is one of the most common chronic dermatologic conditions globally and often significantly affects quality of life. For moderate to severe and treatment-resistant acne, oral isotretinoin remains one…
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INTRODUCTIONPsoriasis is a chronic inflammatory skin condition, affecting approximately three percent of the United States population. While modern therapeutic options for psoriasis have greatly improved symptom management and disease outcomes,…
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