INTRODUCTIONInflammation and photodamage are largely considered the leading contributors to premature skin aging as they lead to decreased collagen content in the skin.1 Collagen, the most abundant protein in the…
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In this issue:Real-World Cases Using Phyto Polydeoxyribonucleotide (PDRN) Serum Integrative skincare refers to a clinician-directed regimen that combines aesthetic procedures with appropriate post-procedure skincare. The novel phyto polydeoxyribonucleotides (PDRN) formulation…
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INTRODUCTIONAtopic dermatitis and prurigo nodularis represent the two most burdensome pruritic inflammatory skin diseases encountered in clinical dermatology. While distinct in morphology, chronicity, and epidemiology, both conditions are united by…
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In this issue:Interleukin-31 in Atopic Dermatitis and Prurigo Nodularis: Pathophysiology, Neuroimmune Mechanisms, and Clinical Efficacy of Nemolizumab This manuscript provides an integrated review of IL-31 pathophysiology in AD and PN…
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INTRODUCTIONEyebrows play an essential role in facial symmetry, communication, and aesthetic identity.1,2 Scarring, or cicatricial, eyebrow alopecia involves a diverse group of inflammatory, autoimmune, infectious, and traumatic processes that destroy…
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INTRODUCTIONHyaluronic acid (HA) filler injection is the second most commonly performed nonsurgical aesthetic procedure globally. HA filler use has risen sharply, driven by advantages over earlier collagen-based fillers, such as…
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INTRODUCTIONKeloids and hypertrophic scars are benign fibroproliferative skin disorders characterized by excessive and disorganized collagen deposition extending beyond the original wound margins, typically arising after cutaneous injury, surgery, inflammation, or…
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INTRODUCTIONAcne vulgaris is a common, chronic dermatologic condition with an estimated global prevalence of 9.4% across age groups.1,2 The condition presents as open or closed comedones, papules, pustules, or nodules…
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INTRODUCTIONThe body contouring market has undergone a significant technological transformation, characterized by a paradigm shift from invasive surgical procedures to advanced noninvasive treatments. Traditionally, liposuction represented the gold standard for…
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INTRODUCTIONSkin aging involves the gradual breakdown of the ECM's structure and function, including collagen fragmentation, elastin disorganization, and loss of ground substances like hyaluronic acid.1,3–5 These changes lead to decreased…
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To the Editor,Wide local excision (WLE) is the current standard of care for treatment of melanoma in situ (MIS).1 Mohs micrographic surgery (MMS) is another surgical treatment used for MIS,…
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INTRODUCTIONPyoderma gangrenosum (PG) is classified as a neutrophilic dermatosis, often presenting as a rapidly enlarging ulcer and associated with inflammatory bowel disease (IBD), specifically ulcerative colitis and Crohn's disease (CD).1…
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