Supplement Individual Article: Pediatric Acne Patients’ Treatment Real-World Case Series Using Skincare as Monotherapy, Adjunctive, and Maintenance Treatment

February 2023 | Volume 22 | Issue 2 | SF376527s3 | Copyright © February 2023


Published online January 31, 2023

Lawrence A. Schachner MD FAAD FAAP,a Anneke Andriessen PhD,b Latanya Benjamin MD FAAD FAAP,c Madelyn Dones MD FAAP,d Ayleen Pinera-Llano MD FAAP,e Linda Keller MD FAAP,f Leon Kircik MD FAAD,g Adelaide A. Hebert MD FAADh

aDivision of Pediatric Dermatology, Department of Dermatology and Cutaneous Surgery, Department of Pediatrics, Leonard M. Miller School of Medicine, University of Miami, FL
bRadboud UMC, Nijmegen and Andriessen Consultants, Malden, The Netherlands
cDepartment of Women's and Children's Health, Florida Atlantic University, Boca Raton, FL
dBaptist Health Hospital, Nicklaus Childrens' Hosptital, Miami, FL
eKing Bay Pediatrics, Maimi, FL, General Pediatrics, Nicklaus Children's Hospital, Miami, FL
fBaptist Health Baptist Hospital, Baptist Health South Miami Hospital, Miami, FL
gIcahn School of Medicine at Mount Sinai, New York, NY; Indiana University Medical Center, Indianapolis, IN; Physicians Skin Care, PLLC Louisville, KY; DermResearch, PLLC Louisville, KY; Skin Sciences, PLLC Louisville, KY
hDepartment of Dermatology and Pediatrics, McGovern Medical School, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX

Neonatal acne rarely presents signs of sexual precocity, virilization, or growth abnormalities.5,6,10-13 Significant neonatal acne may be due to an underlying endocrinologic disease, tumor, or other gonadal/ovarian pathology.5,6 These patients require a workup and a referral to a pediatric endocrinologist.5,6 Neonatal acne typically resolves over a few months without scarring.5 For more complicated cases, off-label topical therapies may be considered.5,6,10-14

CASE 1

A 3-week-old breast- and formula-fed male with neonatal acne on the face and atopic dermatitis (AD) on the scalp (Table 1). Previously, an oatmeal-containing moisturizer was used daily on the boy's face and scalp. The physician informed the parents about the hormonal influences causing the facial eruptions and the presence of AD.5,6,10-14,18 The aim was to establish a skincare regimen using a ceramide-containing baby wash and shampoo and baby moisturizing lotion and cream to promote a healthy skin barrier.14-18 No further treatment was deemed necessary.5,6,10-14 The new parents were receptive to the specific skincare recommendations that cleared acne and AD. After clearance, they continued using the skincare regimen.

CASE 2

A 1-month-old male with neonatal acne on the face, mainly on the cheeks. No skin care was used upon presentation. The treatment comprised hydrocortisone acetate cream 2.5% and econazole nitrate cream 1% for 14 days. Upon follow up, the parent noted no improvement, and as a result, both creams were discontinued. The parent’s education on this condition's transient and treatable nature was followed by the recommendation of a ceramide-containing baby wash and salicylic acid-containing moisturizer cream, which cleared
the neonatal acne.