JDD Special Focus

Skin Cancer

Stay up-to-date on new clinical findings in Skin Cancer  View the latest articles, case reports, supplements, podcast episodes and more!

 

Articles

Basal Cell Carcinoma Gene Mutations Differ Between Asian, Hispanic, and Caucasian Patients: A Pilot Study

Do gene mutations in basal cell carcinoma vary between Hispanic, Asian and Caucasian patients? How do gene mutations in skin of color inform therapy options and course of treatment?

The Potential Efficacy of β-Blockers on Melanoma Survival: A Narrative Review

What is the role of role and status of β-blockers in melanoma management?

A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma

Compare systemic Hedgehog inhibitors (HHIs) sonidegib and vismodegib for efficacy, safety, and pharmacokinetics. [FREE TEXT]

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Case Reports

Basal Cell Carcinoma in the Nasal Vestibule

Basal cell carcinomas (BCC) arise from DNA damage to cells of the basal layer of the epidermis and most commonly in areas of the skin exposed to sunlight or ultraviolet radiation. BCC is the most common skin cancer seen in humans with over 4.3 million cases reported in the United States and is responsible for 3-10% of all cancers annually. We report what we believe to be the first case of this very prevalent skin cancer arising in the nasal vestibule. The lesion was treated with Mohs micrographic surgery and required three stages to obtain histological clearance. Given the location of the tumor, Mohs surgery was chosen due to the procedure’s effectiveness for achieving the highest cure rate with the lowest incidence of tumor recurrence and for preserving as much adjacent healthy tissue as possible

Combination Topical Chemotherapy for the Treatment of an Invasive Cutaneous Squamous Cell Carcinoma

Standard of care for squamous cell carcinoma (SCC) is usually surgical, with either excision or Mohs micrographic surgery. However, surgery may not be ideal for elderly patients with numerous lesions, who are poor surgical candidates or who refuse surgery. Topical 5-fluorouracil (5-FU) and imiquimod have been studied off-label as monotherapies in the treatment of SCC in situ with promising results. However, long-term tumor-free survival rates are still less than with surgical management.

Recurrent Squamous Cell Carcinoma Arising Within a Linear Porokeratosis

Here we report a case of linear porokeratosis with recurrent malignant degeneration to squamous cell carcinoma (SCC) recurring six years after excision of initial SCC. A 79-year-old woman presented with a friable tumor located within a longstanding lesion on her posterior thigh. Six years prior, she was diagnosed with SCC arising within the same lesion, which had been surgically excised with negative margins. Physical examination revealed a 3.5 x 2.7 cm friable tumor on the left proximal posterior thigh.

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Podcast Episodes

Support the (On)cause: A Practical Review of Supportive Oncodermatology

Dr. Mario Lacatoure joins podcast host Dr. Adam Friedman to discuss the array of cutaneous clusters that not only can, but are almost expected to occur during cancer therapy. Learn how even simple OTC products can contribute to both ameliorating and even preventing some of these sequelae.

Identifying Gaps in Sun Protection Perceptions and Use in Native Americans

Skin cancer doesn’t discriminate. We hear that evidenced-based media-friendly line often nowadays to highlight the importance of sun protection in all skin types. But are we really getting that message everywhere it needs to be? Definitely not. Dr. Vivian Shi’s most recent study published in the June 2019 edition of JDD highlights clear shortcomings in the Native American communities in Arizona. Tune in to hear how this study came to light, what unique concerns and issues impede proper sun protection in this group, and tricks to get even a nonbeliever on a photoprotective regimen that he or she can realistically stay on.

Variations in Skin Cancer Screening Practices Among Dermatologist

Dr. Adam Friedman and Dr. Evan Rieder, Assistant Professor of Dermatology at NYU Langone Medical Center and one of the few dermatologists double board certified in dermatology and psychiatry in the U.S., to discuss his recent study entitled “Dermatologist Practices During Total Body Skin Examinations: A Survey Study.” Do we all do it the same? Are we all checking every nook and cranny? Do we need better standardization for our greatest weapon to enable early and life saving skin cancer detection?

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Supplements

Skin Cancer in Hispanics in the United States

The American Cancer Society reported that Cancer remains leading cause of death in Hispanics. Lung cancer for men and breast for women. Non-melanoma skin cancer (NMSC) is the most common malignancy in the United States, over 3.5 million in over 2 million people, incidence rising at about 2.6% per year.

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Dermatology News

JDD HighlightsJDD WebinarsOatsThe Latest
January 25, 2022

The Role of Colloidal Oatmeal in Managing Eczema and Beyond

Sponsored by This webinar highlights the data supporting the mechanism of action of oat in emollients as well as clinical efficacy and safety of its use in atopic dermatitis and…
JDD HighlightsJDD in the MediaThe Latest
January 25, 2022

ANNOUNCEMENT: WebMD Acquires SanovaWorks

NEW YORK, Jan. 25, 2022 /PRNewswire/ -- WebMD Health Corp., an Internet Brands company and a leader in health information services for physicians, other healthcare professionals and consumers, today announced that it…
Atopic DermatitisCOVID 19JDD HighlightsJDD in the MediaPsoriasisThe Latest
January 14, 2022

JDD in the News: Medical Cannabis Products, S. aureus-Based Product for AD

By Allison Sit Practical Dermatology published an article, “Survey: Consumers Interested in Medical Cannabis Products for Inflammatory Skin Disorders,” about the January JDD study, “Consumer Perspectives on and Utilization of…
AcneDerm CommunityDermatology RoundupLasers & Light Devices
January 5, 2022

Dermatology Roundup: International Acne Scarring Consensus & Sunscreen Ban

By Allison Sit An international group of 24 plastic surgeons and dermatologists from 12 countries have collaborated to create a consensus on the treatment of acne scars. Lasers and Surgery…