Issue Archive
February 2025 | Volume 24 | Issue 2
Original Articles
A Multi-Component Reaction Peptide Augmenting the Anti-Aging Benefits of Non-Ablative Laser Procedure
Background: Laser resurfacing is one of the most popular aesthetic procedures that address a wide range of skin conditions and overall skin rejuvenation. To reduce downtime and improve the clinical ef...
Read MoreVisual Assessment Tools and Therapeutic Implications for Acanthosis Nigricans
Acanthosis nigricans significantly impacts individuals with skin of color. No United States Food and Drug Administration (FDA)-approved therapy exists for acanthosis nigricans. This review evaluates v...
Read MoreGuselkumab Efficacy by Psoriasis Disease Severity and Treatment History: VOYAGE 1 and 2 Post Hoc Analyses
Background: The pivotal Phase 3 VOYAGE 1 and VOYAGE 2 studies established the robust efficacy and safety of guselkumab for up to 5 years in patients with moderate-to-severe psoriasis. Here, the long-t...
Read MoreDupilumab Treatment Improves Lichenification in Atopic Dermatitis in Different Age and Racial Groups
Background: Lichenification, common in moderate to severe atopic dermatitis (AD) at any age, is often difficult to treat. This analysis assessed dupilumab vs placebo in AD lichenification by age and r...
Read MoreAntioxidant, Keratolytic, and Hydrating Treatment for Seborrheic Keratoses
Background: Seborrheic keratoses (SKs) are the most common skin lesions to prompt visits to a dermatologist. Patients may be concerned about unsightly appearance, irritation, or the possibility of ski...
Read MoreNon-Surgical Correction of Dermatochalasis Using Microplasma
Background: Dermatochalasis is characterized by the presence of redundant and loose upper eyelid skin, which occurs as part of the aging process and is often considered aesthetically undesirable....
Read MoreA Review of the Safety and Efficacy of Deucravacitinib for Plaque Psoriasis: An Expert Consensus Panel
Background: Psoriasis is a chronic, inflammatory disease associated with numerous negative physical and psychosocial impacts. Deucravacitinib is a novel, selective TYK2 inhibitor approved by the FDA f...
Read MoreSunscreens: Mechanisms and Safety in Depth
Sunscreens play an essential role in preventing skin cancer and photoaging. Nevertheless, concerns about their systemic absorption and environmental impacts persist. In this extensive literature revie...
Read MoreEfficacy and Consumer Perception of Topical Over-the-Counter Regimens Involving Beta-Hydroxy Acid for Acne Vulgaris
The use of alpha-hydroxy acids (AHAs) and beta-hydroxy acids (BHAs) for acne treatment and their integration into daily skincare routines for better cosmetic outcomes has increasingly become a norm, p...
Read MoreBiotin or Pyridoxine Versus Combined Regimen in the Treatment of Onychoschizia
Background: Onychoschizia is characterized by distal nail plate splitting. Several therapeutic approaches exist, most of which are based on case reports or small non-comparative case series. Objectiv...
Read MoreComparing Adherence, Side Effects, and Satisfaction in Oral and Topical Minoxidil: A Cross-Sectional Study
Hair loss disorders negatively impact quality of life. Topical and oral minoxidil are hair loss therapeutics that require daily use to achieve sustained benefits. Patients on topical minoxidil often r...
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Features
Insights Into Demographics, Comorbidities, and Risk Factors in Keloids and Hypertrophic Scars: A Retrospective Study
Hypertrophic scars and keloids represent abnormal wound healing, manifesting as raised scars confined to or extending beyond the wound margin, respectively. Understanding the risk factors associated w...
Read MoreA Review of Management Strategies for Erosive Pustular Dermatosis of the Scalp
Evaluating Quality and Reliability of Most-Viewed TikTok Videos About Spironolactone
Case Reports
An Unusual Case of Psoriasiform Dermatitis Treated With Dual Biologic Therapy and Literature Review
Previously believed to be of distinct immunopathogenesis, atopic dermatitis (AD) and psoriasis (PsO) spectrum may permit immunologic shifts to favor the opposing inflammatory states following biologic...
Read MoreCo-occurring Melanoma in an Active Area of Vitiligo in Skin of Color
The association between vitiligo and melanoma is complex. While the incidence of vitiligo in patients with melanoma is higher, the risk for the reverse, ie, the development of melanoma in a patient wi...
Read MoreUse of Upadacitinib in Refractory Behcet's Disease: Case Report and Systematic Literature Review
Keloidal Morphea: A Unique Variant of Morphea Presenting in a Black Female
Keloidal morphea is a rare variant of cutaneous scleroderma that presents with keloid-like plaques and nodules that occur most commonly on the neck, trunk, and proximal extremities. They occur in the ...
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Departments
FULL SUPPLEMENT: Masterful Topical JAK Inhibitor
Janus kinase (JAK) inhibitors, which have been used in a range of disease states from rheumatology to gastroenterology, have been finally adopted into dermatology. These agents are rapidly changing th...
Read MoreFULL SUPPLEMENT: Scalp Health & the Role of the Scalp Barrier in Dandruff and Seborrheic Dermatitis
Research has shown that scalp and hair health are connected, but the link is not yet fully understood or characterized. Hair growth begins within the hair follicle, about 4 mm deep in the skin.1 The c...
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Supplements
INDIVIDUAL ARTICLE: Ruxolitinib 1.5% Cream and the "Boxed Warning Paradox": Reappraisal of Safety Through the Lens of Pharmacokinetics
Ruxolitinib 1.5% cream is the first-in-class topical Janus kinase (JAK) inhibitor approved for the treatment of atopic dermatitis in patients 12 years of age and older. The US Food and Drug Administra...
Read MoreINDIVIDUAL ARTICLE: Insights on the Impact of Scalp Barrier Condition on Hair Health
Scalp health is essential for healthy hair growth and may be affected by intrinsic or extrinsic factors. Reactive oxygens species are key contributors to aging and can have a detrimental impact on sca...
Read MoreINDIVIDUAL ARTICLE: Etiology, Treatment Challenges, and the Role of Scalp and Haircare in Managing Dandruff
Dandruff and seborrheic dermatitis are associated with a disrupted scalp barrier that contributes to irritation, pruritus, and flaking of the scalp. The flaking and itch associated with dandruff can s...
Read MoreINDIVIDUAL ARTICLE: VEHICLES MATTER: DESIGNED FOR PURPOSE
INDIVIDUAL ARTICLE: Appraisal of Ruxolitinib 1.5% Cream as a First-Line Topical Therapeutic Agent for Adolescents and Adults With Mild-to-Moderate Atopic Dermatitis
Dermatology has entered the long-awaited paradigm shift from steroidal to non-steroidal therapeutics for the topical treatment of atopic dermatitis. Topical Janus kinase (JAK) inhibitors have garnered...
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