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Dec 10
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Straight-Line Vector Planning for Optimal Results With Silhouette InstaLift in Minimally Invasive Tissue Repositioning for Facial Rejuvenation

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INTRODUCTIONFacial aging may be apparent through the appearance of wrinkles, volume loss, and sagging. For sagging in particular, reductions in elastin and the supportive capacity of collagen result in greater…
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Dec 10
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Patient Reported Improvement in Quality of Life Associated With Successful Laser Hair Reduction at Hemodialysis Site With 1064-nm Nd:YAG Laser

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INTRODUCTIONLaser hair reduction (LHR) is a well-established modality for a wide range of medical indications, including hidradenitis suppurativa, pseudofolliculitis barbae and hirsutism.1 Traditional hair reduction treatments include shaving, plucking, waxing,…
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Dec 10
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Combination Ablative Approach to Laser Therapy in Advanced Aging of the Face

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INTRODUCTIONFacial aging is multifactorial. Photodamage, loss of subcutaneous fat, reduced skin elasticity, periosteal remodeling, and the repetitive action of the facial muscles contribute to the visible signs of aging –…
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Dec 10
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Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib

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INTRODUCTIONAlopecia areata (AA) is a chronic autoimmune disease involving the hair follicle with a high relapse rate and variable response to traditional therapies that nonspecifically target the immune system. Janus…
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Dec 10
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The Evaluation of Cutaneous Metastasis from an Unknown Primary

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INTRODUCTIONA 66-year-old man presented to the clinic with a rapidly expanding nodule on his right forehead. Examination revealed a 2 cm soft subcutaneous nodule that was clinically consistent with an…
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Dec 10
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Severe Oral Mucositis: A Rare Adverse Event of Pembrolizumab

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CASE REPORTA 78-year-old Chinese woman with a history of metastatic lung adenocarcinoma presented to the hospital for evaluation of an acute, painful erosive eruption involving the intraoral mucosa and lips…
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Dec 10
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Margin Assessment for Punch and Shave Biopsies of Dysplastic Nevi

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INTRODUCTIONBiopsies of atypical melanocytic nevi are among the most commonly performed procedures by dermatologists. Once biopsied, specimens are examined by dermatopathologists for diagnosis, grading of atypia, and often the reporting…
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Dec 10
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Yes to Appropriate Compounding, No to Illegal Compounding

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Dermatology is often described as a “visual” specialty. While it is true that many of our diagnoses can be made based on a relatively quick recognition of morphology, such a…
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Dec 10
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The Practice of Compounding, Associated Compounding Regulations, and the Impact on Dermatologists

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INTRODUCTIONMedication compounding gained national attention in 2012 after contaminated compounded medications produced in the New England Compounding Center caused an infectious outbreak that led to several fatalities. In addition, rising…
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Dec 10
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Understanding the Complexities of Compounding

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Dec 10
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Long-Term Efficacy of Guselkumab for the Treatment of Moderate-to-Severe Psoriasis: Results from the Phase 3 VOYAGE 1 Trial Through Two Years

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INTRODUCTIONPsoriasis is a chronic immune-mediated disease with predominant skin involvement. Multiple randomized studies of biologic agents have demonstrated the need for continual treatment.1-9 Open-label extensions of clinical trials conducted to…
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Dec 10
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Mechanisms Underlying the Clinical Effects of Apremilast for Psoriasis

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INTRODUCTIONPsoriasis is a chronic, systemic, inflammatory disease that affects 1% to 4% of the population worldwide,1 including an estimated 7.4 million US adults.2,3 Many patients report that psoriasis has a…
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