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Safety and Effectiveness of Two Reconstitution Volumes of Poly-L-Lactic Acid for Correction of Décolletage Wrinkles

By June 26, 2026No Comments

Beyond the Face: New JDD Data on Décolletage Rejuvenation With PLLA-SCA

Have you read this article from the JDD? A new study is drawing attention to an area that aesthetic patients are asking about more often, the décolletage. As facial rejuvenation improves, concern about untreated aging skin on the chest is becoming more visible in cosmetic consultations, and this JDD article looks at one potential option worth noting.

This 9 month open label study evaluated poly L lactic acid, or PLLA SCA, for correction of décolletage wrinkles using two different reconstitution volumes. Women with moderate to severe wrinkles were randomized to receive treatment with either 8 mL or 17 mL sterile water for injection plus lidocaine, with up to four sessions spaced one month apart. The study assessed wrinkle severity, global aesthetic improvement, patient satisfaction, skin quality, and safety.

For practicing dermatologists and dermatology healthcare professionals, the findings may be of interest because both treatment approaches showed meaningful improvement over time. Most participants demonstrated at least a one point improvement in wrinkle scores, and global aesthetic ratings were strong in both groups. Patient satisfaction also remained high, with many subjects reporting improvement in the appearance, texture, smoothness, and radiance of the décolletage skin.

Safety findings were also reassuring, with only one treatment related adverse event reported and no serious events or discontinuations. While this was a small study, it adds to the growing conversation around regenerative biostimulators and aesthetic treatment options for the neck and chest area.

If you are following the latest developments in décolletage rejuvenation, PLLA SCA, and nonfacial aesthetic care, this JDD article deserves a closer look.

Blog write-up assisted by AI