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Dec 10
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Using a New Photo Scale to Compare Product Integration of Different Hyaluronan-Based Fillers After Injection in Human Ex Vivo Skin

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INTRODUCTIONThe gel-based dermal filler market sees new products entering the market each year. The most common type of fillers is the hyaluronan (HA) cross-linked gels. For instance, the European market…
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Dec 10
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Once-Daily Oral Sarecycline 1.5 mg/kg/day Is Effective for Moderate to Severe Acne Vulgaris: Results from Two Identically Designed, Phase 3, Randomized, Double-Blind Clinical Trials

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IntroductionBroad-spectrum tetracycline-class antibiotics, such as minocycline and doxycycline, are considered first-line therapy in the management of moderate to severe acne.1 In addition to their antimicrobial activity, tetracycline-class antibiotics have anti-inflammatory…
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Dec 10
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A Single Site, Open Label Clinical Trial, Evaluating the Duration, Efficacy, and Safety of a Novel Lip Plumper

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INTRODUCTIONFull and well-defined lips impart a sense of youth, attractiveness, and health.1 While the ideal lip varies across cultures, the appropriate upper to lower lip balance and a defined vermillion…
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Dec 10
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Artificial Intelligence for the Objective Evaluation of Acne Investigator Global Assessment

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INTRODUCTIONThe measurement and grading of acne severity is a recognized challenge1-3, since it is known to depend on the number and type of lesions and the extent of involvement. The…
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Dec 10
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A Comparative Analysis of Electric and Radiofrequency Microneedling Devices on the Market

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INTRODUCTIONMicroneedling was first described in 1995 by Orentreich and Orentreich for the treatment of atrophic scars and wrinkles.1 The local injury induced by dermal penetration of microneedling causes release of…
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Dec 10
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Facial Volumetric Structural Rejuvenation: A Natural Approach to Restoring Youthfulness and Preventing Aging

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When rejuvenating the face with soft tissue fillers, one must consider its structural framework, and patient specific goals/needs holistically to achieve natural results.1-3 I have developed a distinct methodology called…
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Dec 10
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Approach to Skin Lightening in Patients With Melasma

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I read with interest the informative article by Spencer et al1 that describes the efficacious use as a novel skin lightening agent (LumaPro-C) for the treatment of patients with melasma.…
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Dec 10
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Epidemiology of Skin Diseases in a Diverse Patient Population

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BACKGROUNDStudies regarding epidemiology are a vital component in recognizing areas of interest, allocating resources, and finding areas of further research. As our society becomes more diverse, epidemiological studies accurately representing…
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Dec 10
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Effect of an Emollient on the Mycobiome of Atopic Dermatitis Patients

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INTRODUCTIONAtopic dermatitis (AD) is a chronic inflammatory skin disorder that results in areas of dry, itchy skin.1,2 Several cultivation-dependent and independent studies have identified changes in the composition of microbial…
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Dec 10
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Topical Antibacterial Agent for Treatment of Adult and Pediatric Patients With Impetigo: Pooled Analysis of Phase 3 Clinical Trials

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INTRODUCTIONImpetigo is the most common bacterial skin infection in children, although it can occur at any age.1-6 As impetigo is highly contagious, the condition is of particular concern in daycare…
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Dec 10
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Efficacy of Systemic Dapsone Treatment for Pyoderma Gangrenosum: A Retrospective Review

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INTRODUCTIONPyoderma gangrenosum (PG) is a non-infectious neutrophilic dermatosis commonly associated with underlying systemic disease. Its etiology is postulated to be a result of abnormal neutrophil function.1 While treatment centers on…
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Dec 10
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Safety and Efficacy of a Once-Daily Halobetasol Propionate 0.01% Lotion in the Treatment of Moderate-to-Severe Plaque Psoriasis: Results of Two Phase 3 Randomized Controlled Trials

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INTRODUCTIONPsoriasis is a chronic, immune-mediated disease that affects approximately 2% of the population.1-3 The use of topical therapy is a key component in the management of almost all psoriasis patients.…
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