INDIVIDUAL ARTICLE: Pediatric Atopic Dermatitis Patient Cases Integrating Ceramides-Containing Cleansers and Moisturizers into Prescription Treatment and Maintenance Approaches

December 2023 | Volume 22 | Issue 12 | SF389716s3 | Copyright © December 2023


Published online November 28, 2023

Lawrence A Schachner MD FAAD FAAPa, Anneke Andriessen PhDb, Madelyn Dones MD FAAPc, Mercedes E Gonzalez MD FAADd, Linda Keller MD FAAPe, Karan Lal MD MS FAADf, Peter Lio MD FAADg, Ayleen Pinera-Llano MD FAAPh, Latanya Benjamin MD FAAD FAAPi

aDivision of Pediatric Dermatology, Department of Dermatology and Cutaneous Surgery, Department of Pediatrics, Leonard M. Miller School of Medicine, University of Miami, FL
bRadboud UMC, Nijmegen and Andriessen Consultants, Malden, The Netherlands
cBaptist Health Hospital, Nicklaus Childrens’Hosptital, Miami, FL
dMedical Director, Pediatric Skin Research, Assistant Professor Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery at the University of Miami Miller School of Medicine Miami, FL
eBaptist Health Baptist Hospital, Baptist Health South Miami Hospital, Miami, FL
fSchweiger Dermatology Group, New York, NY
gClinical Assistant Professor of Dermatology & Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL
hKing Bay Pediatrics, Maimi, FL, General Pediatrics, Nicklaus Children's Hospital, Miami, FL
iAssociate Professor of Pediatric Dermatology, Department of Women's and Children's Health, Florida Atlantic University, Boca Raton, FL

His face was treated with CER-containing hydrating cleanser once daily, CER-containing cream twice daily, and pimecrolimus 1% cream nightly. In the morning, he was advised to use a CER-containing hydrating mineral sunscreen on the face. Once the AD had cleared, he continued with the CER-containing skincare regime and the CER-containing hydrating mineral sunscreen in the morning. 

The main lessons learned: AD may flare after a long period without flares when triggers such as excessive sun exposure, chemicals used in a swimming pool, or xerosis lead to flaring. It is important to start educating patients and parents about AD and maintaining a healthy skin barrier using frequent and ongoing CER-containing skincare and sun protection with a CER-containing hydrating mineral sunscreen. 

Patient 5: This 6-year-old boy with Fitzpatrick phototype I with a family history of asthma and AD presented with recurrent pruritic flares on his arms and body, interfering with his sleep (Table 5).