INDIVIDUAL ARTICLE: Pediatric Atopic Dermatitis Patient Cases Integrating Ceramides-Containing Cleansers and Moisturizers into Prescription Treatment and Maintenance Approaches

December 2023 | Volume 22 | Issue 12 | SF389716s3 | Copyright © December 2023


Published online November 28, 2023

Lawrence A Schachner MD FAAD FAAPa, Anneke Andriessen PhDb, Madelyn Dones MD FAAPc, Mercedes E Gonzalez MD FAADd, Linda Keller MD FAAPe, Karan Lal MD MS FAADf, Peter Lio MD FAADg, Ayleen Pinera-Llano MD FAAPh, Latanya Benjamin MD FAAD FAAPi

aDivision of Pediatric Dermatology, Department of Dermatology and Cutaneous Surgery, Department of Pediatrics, Leonard M. Miller School of Medicine, University of Miami, FL
bRadboud UMC, Nijmegen and Andriessen Consultants, Malden, The Netherlands
cBaptist Health Hospital, Nicklaus Childrens’Hosptital, Miami, FL
dMedical Director, Pediatric Skin Research, Assistant Professor Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery at the University of Miami Miller School of Medicine Miami, FL
eBaptist Health Baptist Hospital, Baptist Health South Miami Hospital, Miami, FL
fSchweiger Dermatology Group, New York, NY
gClinical Assistant Professor of Dermatology & Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL
hKing Bay Pediatrics, Maimi, FL, General Pediatrics, Nicklaus Children's Hospital, Miami, FL
iAssociate Professor of Pediatric Dermatology, Department of Women's and Children's Health, Florida Atlantic University, Boca Raton, FL

Patient 3: This otherwise healthy 9-year-old girl with Fitzpatrick phototype VI has had long-standing AD since she was one year old (Table 3). She had a history of seasonal allergies. She was previously treated with hydrocortisone cream 1% and skincare comprising cocoa butter and coconut oil. The patient reports being embarrassed by the dark patches on her skin and does not want to wear shorts. She received mometasone 0.1% ointment twice daily until clear, followed by crisaborole application once daily. In addition, CER-containing hydrating cleanser and moisturizer were applied twice daily. At the 8-week follow-up, her skin condition had markedly improved, with the skin of her neck cleared.

The main lessons learned: Clinically, AD may present differently in richly pigmented skin. Nuanced expression of erythema and post-inflammatory pigment alterations may be observed in richly pigmented patients with AD.12,13  Black patients may show more frequent follicular accentuation, lichenoid morphologies, and papulonodular presentations.12,13 Educating the patient and parents about maintaining a healthy skin barrier and reducing inflammation to prevent sequelae is essential. In richly pigmented skin, hyper or hypopigmentation occurs more frequently than in AD patients with white skin.12,13