INDIVIDUAL ARTICLE: Algorithm for Nonenergy and Injectable Treatment Pre-/Post-Procedure Measures

November 2021 | Volume 20 | Issue 11 | Supplement Individual Articles | ss3s | Copyright © November 2021


Published online November 1, 2021

Michael Gold MD FAAD,a Anneke Andriessen PhD,b David J. Goldberg MD JD FAAD,c Komel V.Grover MBA,d Shasa Hu MD FAAD,e Z. Paul Lorenc MD FACS,f Stephen H. Mandy MD FAADg

aGold Skin Care Center, Nashville, TN; Vanderbilt University School of Medicine and Nursing, Nashville, TN
bRadboud UMC Nijmegen, Andriessen Consultants, Malden, NL
cSkin Laser & Surgery Specialists of NY and NJ, Hackensack, NJ; Icahn School of Medicine at Mt. Sinai, New York, NY
dSwiss American CDMO, Dallas, TX
eUniversity of Miami Miller School of Medicine, Miami, FL
fLorenc Aesthetic Plastic Surgery Center, New York, NY; Lenox Hill Hospital, New York, NY
gDr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL

were reported anywhere from 0.04% to 0.2%.37 Biofilms are particularly problematic as they are challenging to treat.36 Most post-procedure infections are associated with pain, swelling, delays healing, and may lead to scarring and require an in-office evaluation.37-39,51-56

Few injectors regularly use prophylactic therapy before or after injectable treatment. When products were used to avoid or manage AEs, the heterogeneity of the measures prohibited identifying or establishing a standard.61

Given the large amount of aesthetic injectable treatments performed per year, the incidence rates of AEs, and the lack of any standard before, during, and after treatment measures, AE risk reduction must direct efforts at validating and standardizing these measures.24,25

Post-procedure, the advisors recommend avoidance of sun exposure, topical retinoids, and ascorbic acid/hydroxy acids to reduce the risk of proinflammatory pigment alteration or inflammation. They further advised to delay hair removal (eg, shaving, depilatories) between 24-hours post-procedure to two weeks post-procedure, depending on the procedure and specific patient requirements. Patients are advised to keep the treated site clean using a gentle cleanser and to keep the skin moist using a fragrance-free moisturizer (Table 4).

Various products are provided by clinicians to patients or recommended to use at home post-aesthetic nonenergy and injectable procedures. These products include white petrolatum, topical antiseptic cream or ointment, HOCl containing products, or products containing arnica or bromelain.24,25

Currently, there are no standards of practice for clinicians when using before, during, and after procedural measures for nonenergy and injectable treatments.24,25 Given the large amount of nonenergy and injectable treatments performed per year, the incidence rates of AEs, and the lack of standard before, during, and after procedural measures, AE risk reduction must direct efforts at validating and standardizing these procedural measures.

LIMITATIONS

Statements used in the algorithm were based on a mix of data and expert opinion. While alternatives for before and after measures for nonenergy-based-device and injectable treatments could exist, the statements suggest best practices developed from a panel of expert clinicians supported by peerreviewed literature. However, there is a lack of literature that explicitly addresses before and after measures for nonenergybased- device and injectable treatments.

CONCLUSIONS

The algorithm designed to support optimal treatment outcomes addresses measures for prevention before, during, and after nonenergy and injectable facial treatments.

Prevention includes sun avoidance and the use of a broadspectrum sunscreen with an SPF of at least 30. Oral antiviral prophylaxis is recommended for those with a history of HSV-1. Stabilized HOCl has benefits for pre-, peri-, and postprocedure management combined with an emollient. A purpose-designed antimicrobial option for preparing the skin, as well as a topical post-treatment option, would be welcome.

CONCLUSIONS

Swiss American, LLC supported the research and development of the algorithm with an unrestricted educational grant.

The pre-/post-procedure measures project group (authors) produced three published surveys: 1) Laser and energy devices, 2) Nonenergy devices, and 3) Injectables and one algorithm on laser and energy devices. The current algorithm addresses pre-/post-procedure measures for nonenergybased and injectable skin treatments.

The information obtained from the survey on nonenergy devices and injectables is used for the algorithm.

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