Facial Aging Improvement Case Study Using a Novel Combination of Retinol, Niacinamide, and Terminalia Chebula

July 2022 | Volume 21 | Issue 7 | 784 | Copyright © July 2022


Published online June 30, 2022

Marc Z. Handler MDa,b,c, Alison Adams-Woodford BA LEd, Patty Ayres LE CMLTe, Giorgiana Giancola PhDf, Isabel Diaz BAg

aDepartment of Dermatology, Metropolitan Hospital, New York, NY
bDepartment of Dermatology, Rutgers New Jersey Medical School, Newark, NJ
cDermatology, Hackensack Meridian School of Medicine, Nutley, NJ
dR&D and Communications, Physicians Care Alliance (PCA) Skin, Scottsdale, AZ
ePhysicians Care Alliance (PCA) Skin, Scottsdale, AZ
fScientific Affairs, Colgate-Palmolive Company, Piscataway, NJ
gDermal Clinical Research, Colgate-Palmolive Company, Piscataway, NJ

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5. Kang S, Duell EA, Fisher GJ, et al. Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. J Invest Dermatol. 1995;105(4):549-556.
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7. Gehring W. Nicotinic acid/niacinamide and the skin. J Cosmet Dermatol. 2004;3(2):88-93.
8. Swindell WR, Bojanowski K, Chaudhuri RK. A standardized Terminalia chebula fruit extract alters the expression of genes associated with skin architecture and barrier formation. Eur J Dermatol. 2020;30(5):469-492.

AUTHOR CORRESPONDENCE

Alison Adams-Woodford BA LE aadams@pcaskin.com
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