Importantly, the treatment effects of aboBoNT-A in this study translated into high rates of subject satisfaction, persisting for up to 6 months; ≥91% were satisfied with the aesthetic outcome of their treatment, ≥98% found the results natural-looking, and ≥77% reported broader positive effects of treatment such as feeling more attractive and feeling better about themselves. The FACE-Q scale results confirmed improvement in both satisfaction with GL appearance and psychological well-being, which has also been shown in prior studies with different dilutions of aboBoNT-A.15
Overall, the results from this new dilution study confirmed those obtained in the previously published Phase IV study3 comparing GL treatment with aboBoNT-A using the 0.1 mL versus 0.05 mL injection volume. By this study, we have even more data showing the safety and efficacy of treatment with aboBoNT-A, confirming the rapid onset, long duration, and high subject satisfaction. The safety profile was maintained and there were no signs of increased local spread of toxin with the higher dilution and larger injection volume.
Funding: This study was sponsored by Q-Med AB, a part of Galderma.
Presented at Maui Derm 25–29 January 2021
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