The Effects of a Daily Skincare Regimen on Maintaining the Benefits Obtained from Previous Chemical Resurfacing Treatments

September 2016 | Volume 15 | Issue 9 | Features | 1145 | Copyright © September 2016


Suzanne Bruce MD,a Wendy Roberts MD,b Craig Teller MD,c and Lora Colvan BSd

aSuzanne Bruce and Associates, Houston, TX
bRancho Mirage Dermatology, Rancho Mirage, CA
cBellaire Dermatology Associates, Bellaire, TX
dMDRejuvena, Inc., San Diego, CA

table 6
Photographs taken before and after the 12-week continuation treatment are presented for representative subjects in Figure 4, 5 and 6 who previously received MELA, AGE and MELA treatments respectively.
Safety assessments revealed no adverse events or other safety issues experienced by any of the subjects during the continuation treatment.

DISCUSSION

A daily skin care regimen consisting of a proper cleanser, moisturizer, retinoid, and sunscreen has multiple beneficial effects7-12. These clinical benefits include minimizing disruption in the skin barrier, hydration of the stratum corneum, maintaining optimal pH, improvement in photoaging of the face (reduction in wrinkling, mottled hyperpigmentation, skin roughness, tone and laxity) and protection against UV-induced erythema, sunburn and skin cancer. Topical tretinoin in particular has demonstrated significant improvement in multiple clinical signs of photodamaged skin.9, 10
For more dramatic results, chemical peels that rely on skin exfoliation have commonly been used, however deep peels can be associated with long healing time and potential for complications.3, 4 Treatments based on the concept of creating skin resurfacing via controlled inflammation have been developed to successfully address skin disorders such as aging, hyperpigmentation, acne, and chronic redness. AGE and MELA resurfacing treatments have demonstrated improvements in skin condition in women with signs of photoaging and hyperpigmentation, respectively, with minimal discomfort. The goal of the present study was to demonstrate that a daily treatment regimen of customized skin care products could maintain the benefits achieved from AGE, and MELA skin resurfacing treatments.
The results of this continuation study demonstrate that the use of a daily skin care regimen (including the MDRejuvena Rejuvaphyl Rejuvenating Complex) not only maintains but can enhance the beneficial effects of skin resurfacing treatments for at least 12 weeks. All of the physician assessments, and all but one of the subject assessments, indicated overall improvement compared to baseline in facial skin condition after 12 weeks of MDRejuvena product use following successful skin resurfacing treatments.

DISCLOSURES

Lora Colvan is employed by MDRejuvena, Inc.

REFERENCES

  1. Coleman WP 3rd, Brody HJ. Advances in chemical peeling. Dermatol Clin. 1997;15:19–26.
  2. Fischer TC, Perosino E, Poli F, Viera MS, Dreno B. Chemical peels in aesthetic dermatology: an update 2009. J Eur Acad Dermatol Venereol. 2010;24(3):281-92.
  3. Landau, M. Chemical peels. Clinics in Dermatol 2008;26:200-208.
  4. Rendon MI, Berson DS, Cohen JL, et al. Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing. J Clin Aesthetic Dermatol 2010;3:32-43.
  5. Sigler ML, Stephens TJ. Assessment of the safety and efficacy of topical copper chlorophyllin in women with photodamaged facial skin. J Drug Dermatol. 2015;14:401-4.
  6. McCook JP, Dorogi PL, Vasily DB, Cefalo DR. In vitro inhibition of hyaluronidase by sodium copper chlorophyllin complex and chlorophyllin analogs. Clinical, Cosmetic and Investigational Dermatology. 2015;8:443-8.
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