The current objective criterion for primary endpoints in clinical trials for psoriasis is Psoriasis Area Severity Index 75, as defined by the Food and Drug Administration and clinical trials sponsored…

Erythema elevatum diutinum (EED) is a disease characterized by red to yellow cutaneous papules, nodules, and plaques distributed mainly over extensor surfaces. Histologically, there is leukocytoclastic vasculitis with fibrinoid necrosis…

INTRODUCTION Psoriasis is a common immune-mediated skin disorder, estimated to affect 3-4% of the United States population.1 The pathogenesis of psoriasis is a multifactorial, resulting from a combination of genetic…

INTRODUCTION Paraneoplastic pemphigus (PNP) is an autoimmune blistering disease characterized clinically by painful erosive mucositis and a polymorphous skin eruption. The diagnosis of PNP is based on this distinctive clinical…

INTRODUCTION Atopic dermatitis (AD) is a chronic inflammatory skin disorder that is estimated to affect 15% to 30% of children and 2% to 10% of adults in developed countries.1 Disease…

INTRODUCTION Psoriasis is an immune-mediated chronic inflammatory skin disease characterized by red, scaly plaques that is attributed to aberrant keratinocyte differentiation and alterations in adaptive and innate immune responses.1,2 Approximately…

INTRODUCTION Seborrheic keratosis (SK) is one of the most common dermatologic lesions, affecting 83 million Americans,1 and is one of the most common skin tumors seen by dermatologists in everyday…

INTRODUCTION In an article published in 1999, Ratner and Colleagues stated that “Digital photography is transforming the specialty of dermatology, and the World Wide Web will serve as the medium…

INTRODUCTION Psoriasis is a chronic, inflammatory autoimmune disease that ffects about 3% of the general population in the United States with 17% suffering from moderate to severe psoriasis.1 Psoriasis is…

INTRODUCTION Skin fungal infections occur globally with the causative agents being dermatophytes, yeasts, and molds. Infection results from contact with infected humans, animals, soil, or fomites. Most skin infections are…

BACKGROUND Originally described by Bateman in 1817 as dark purple blotches of irregular form and various magnitude, senile purpura is the subcutaneous disruption of blood vessels that result from skin…