INTRODUCTION Alopecia areata (AA) is an organ-specific, T-cell mediated autoimmune disease of anagen-stage hair follicles. A wide range of clinical presentations can occur, from a single patch of hair loss…

INTRODUCTIONApoptosis or programmed cell death is a central mechanism for maintaining homeostasis. This natural process of cell removal enables the body to rid itself of selected cells safely and effectively.1…

Founded in 1956, the University of Miami Department of Dermatology and Cutaneous Surgery has a storied past and prides itself on clinical excellence and innovative contributions to the field of…

INTRODUCTION Tacrolimus ointment, a topical calcineurin inhibitor, is a common corticosteroid-sparing agent frequently used for atopic dermatitis.1 Topical tacrolimus has also been used to treat seborrheic dermatitis, contact dermatitis, psoriasis,…

An 86-year-old Caucasian female with no significant past medical history presents with a 5-centimeter exophytic ulcerated nodule, as shown in Image A. Biopsy is performed and shows peripheral palisading, retraction…

INTRODUCTIONThese tables review the inheritance patterns, involved genes, and clinical findings of the many hereditary syndromes associated with an increased risk of keratinocyte carcinomas. While these genodermatoses present with complex…

CASE REPORTA 62-year-old man presented to dermatology for a pruritic rash confined to the purple pigment in his tattoo that had started three years previously. Aside from being Hepatitis C…

CASE REPORTA 61-year-old Cuban man presented to our dermatology clinic with multiple pigmented lesions localized to the right side of his face and body. The patient reported a history of…

ADVANCED STAGE MELANOMAImmunotherapy Study for Patients With Stage IV Melanoma Sponsored by NewLink Genetics Corporation, the main objective of this study is to determine the safety and clinical response rate…

KYTHERA Biopharmaceuticals Announces FDA Approval of KYBELLA™ KYTHERA Biopharmaceuticals, Inc. (Nasdaq:KYTH) announced today that the U.S. Food and Drug Administration (FDA) has approved KYBELLA™, also known as ATX-101, “for improvement in…

This July 2015 issue of JDD highlights the broad and diverse world of wound healing/care. The manuscripts here in display the breadth of research, management options, and limitations in the…

Clinical Case A 63-year-old white male with diabetes mellitus type II returns to your clinic for follow-up of non-healing neuropathic diabetic foot ulcers. He has not responded to multiple wound…