The Department of Dermatology at the University of Oklahoma Health Sciences Center came into existence in 1916 and is quickly approaching one century of providing healthcare to the citizens of…
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DISCLOSURES The author has no relevant conflicts of interest to disclose.AUTHOR CORRESPONDENCEJulie Nguyen MDJulie-Nguyen@ouhsc.edu
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CASE REPORTA 66-year-old African-American female presented with a two centimeter lichenified, scaly, and excoriated plaque on the left areola (Figure 1). The asymptomatic plaque had been present for less than…
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Merck and MK-3475 for Advanced Melanoma Merck has announced that the FDA has accepted for review the Biologics License Application (BLA) for MK-3475, Merck’s investigational anti-PD-1 antibody, for the treatment…
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Acne is perhaps the most prevalent skin disease in Western societies,1 yet our understanding of it still remains largely incomplete. We know that the primary pathogenic factors in acne vulgaris…
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Re-evaluating Treatment Targets in Acne Vulgaris: Adapting to a New Understanding of Pathophysiology
INTRODUCTION Two primary factors are changing current approaches to the management of acne vulgaris (AV): the continuously evolving role of Propionibacterium acnes in the pathophysiology of AV and emerging evidence…
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INTRODUCTIONEpidemiologyPublished practice and community-based survey studies have reported that acne is the most frequent dermatologic condition in populations with skin of color, including blacks (in New York, NY;1 Washington, DC;2…
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INTRODUCTION Antibiotic resistance has become a global priority, and the science ministers of the G8 countries have deemed it to be a “major health security challenge of the 21st century.â€1…
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Actinic keratosis (AK) is a premalignant skin condition typically seen almost exclusively in Caucasians, due to their fair skin. AKs develop on chronically sun-exposed areas such as the face, the…
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Biologic agents are complex protein monoclonal antibodies such as adalimumab and ustekinumab, and genetically engineered recombinant fusion proteins such as etanercept. These agents have added greatly to the therapeutic armamentarium…
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INTRODUCTIONHerpes simplex virus (HSV) is the most widely spread virus in the herpes virus family. About one billion people worldwide have been infected with herpes viruses. Orofacial herpes most commonly…
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