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Dec 10
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Psoriasis: The New and the Old

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Treating patients with severe psoriasis is not nearly as frustrating as it used to be. In this issue, two articles describe the use of ustekinumab for psoriasis. Elizabeth Wilder and…
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Dec 10
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Therapeutic Update on Hyperhidrosis

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Hyperhidrosis is defined as non-physiological, excessive sweating that is not caused by physical activity, which occurs in a localized, symmetrical distribution. It affects from 2.8% - 5% of the population…
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Dec 10
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Sorafenib-Associated Psoriasiform Eruption in a Patient With Hepatocellular Carcinoma

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As the use of new chemotherapeutic agents becomes more common, the associated side effects increase. Sorafenib tosylate (Nexavar® tablets, Bayer Healthcare Pharmaceuticals Inc.) is approved for use in the treatment…
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Dec 10
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Dramatic Clearance of HIV-Associated Bowenoid Papulosis Using Combined Oral Acitretin and Topical 5% Imiquimod

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Bowenoid papulosis (BP) is an uncommon squamous intraepithelial neoplasia, which manifests as an eruption of flesh colored or hyperpigmented verrucous papules that may become confluent plaques, involving the genitalia and…
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Dec 10
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The Basic Science of Natural Ingredients

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INTRODUCTION Herbal medicine, also referred to as botanical medicine and phytomedicine, has steadily gained popularity as an alternative to conventional, synthetic drug use.1 In 2007, 1 out of 4 adults…
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Dec 10
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Ustekinumab Treatment for Psoriasis in 119 Patients Maintained on Therapy for a Minimum of One Year: A Review

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INTRODUCTIONPsoriasis is a chronic and complex genetic immune-mediated disease affecting up to 2% of the US population.1 The pathogenesis of psoriasis stems from dysregulated inflammation, which leads to hyperproliferation of…
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Dec 10
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A Randomized, Double-Blinded Trial Evaluating the Efficacy and Tolerability of Vectical Ointment (Calcitriol 3 mcg/g Ointment) When Compared to Betamethasone Diproprionate Ointment (64 mg/g) in Patients With Nail Psoriasis

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INTRODUCTION Psoriasis is a chronic, incurable skin disease affecting millions of people worldwide. Nail abnormalities occur concomitantly in 50% of patients with psoriasis, with a lifetime incidence of 80% to…
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Dec 10
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Trends in Systemic Psoriasis Treatment Therapies from 1993 Through 2010

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INTRODUCTIONA 2004 study determined that the prevalence of diagnosed psoriasis was 3.15%, which is the equivalent of approximately 5 million adults, while the National Psoriasis Foundation estimates that the number…
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Dec 10
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A Randomized, Prospective, Sham-Controlled Study of Localized Narrow-Band UVB Phototherapy in the Treatment of Plaque Psoriasis

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INTRODUCTION Psoriasis is a chronic autoimmune disease that affects 2-3% of adults.1 Despite newer oral and injectable systemic treatment options, phototherapy remains prevalent in disease therapy. Ultraviolet-B (UVB) phototherapy involves…
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Dec 10
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The Use of Self-Administered Subcutaneous Methotrexate for the Treatment of Psoriasis

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INTRODUCTIONWith nearly 50 years of use, methotrexate is a mainstay of therapy for psoriasis. Appropriate patient selection and careful monitoring provides safe and reliable use for a reasonable cost.1-4 Methotrexate…
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Dec 10
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Tumor Necrosis Factor Inhibitor Therapy and Myocardial Infarction Risk in Patients With Psoriasis, Psoriatic Arthritis, or Both

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INTRODUCTION Psoriasis is a chronic skin condition affecting approximately 2-3% of the U.S. population and worldwide.1 About 15-40% of those with psoriasis also have psoriatic arthritis. Those with psoriatic arthritis…
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Dec 10
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Targeted Therapy for Cutaneous Oncology: A Review of Novel Treatment Options for Non-Melanoma Skin Cancer: Part I

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INTRODUCTIONAn evolving theme in the field of cutaneous oncology is the use of personalized or targeted therapy for the treatment of advanced disease. Targeted therapy is the identification of the…
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