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Dec 10
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The Quality of Life Impact of Acne and Rosacea Compared to Other Major Medical Conditions

By No Comments
INTRODUCTIONAcne vulgaris and rosacea can have a profound impact on health-related quality of life (HRQL). A joint project by the American Academy of Dermatology Association and the Society for Investigative…
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Dec 10
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Improvement in Facial Erythema Within 30 Minutes of Initial Application of Brimonidine Tartrate in Patients With Rosacea

By No Comments
INTRODUCTION Rosacea is a chronic inflammatory skin disorder that most commonly presents with transient or persistent erythema in the central facial region with additional cutaneous symptoms including telangiectasia, papules and…
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Dec 10
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Cutaneous Tolerability to Tretinoin Shows Little Variation With Fitzpatrick Skin Type

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INTRODUCTIONAcne vulgaris is one of the most common conditions encountered in dermatology and affects individuals across all racial and ethnic groups.1 However, there is little known regarding variation in response…
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Dec 10
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A Retrospective Analysis of 72 Patients on Prior Efalizumab Subsequent to the Time of Voluntary Market Withdrawal in 2009

By No Comments
INTRODUCTION Psoriasis is a systemic inflammatory disease effecting roughly 2% of the population.1,2 The effects of psoriatic skin disease have been shown to cause significant quality of life impairment equivalent…
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Dec 10
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Only Skin Deep: Optimism and Public Self-Consciousness Did Not Associate With the Placebo Response in a Dermatology Clinical Trial

By No Comments
INTRODUCTIONIn clinical trials, the placebo has an essential role as a comparison set point for various therapies and drugs. Moreover, the placebo response ultimately determines how randomized controlled trials are…
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Dec 10
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The Effect of Desonide Hydrogel on Pruritus Associated With Atopic Dermatitis

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INTRODUCTION Atopic dermatitis (AD) or eczema is a common inflammatory skin disease with a relapsing remitting course. Clinically, it is marked by xerosis and prutitus.1 Current estimates suggest that up…
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Dec 10
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Systematic Review of Vismodegib Toxicity Profile in the Treatment of Advanced Basal Cell Carcinomas Compared to Other Systemic Therapies in Dermatology

By No Comments
INTRODUCTIONVismodegib is a first-in-class FDA-approved oral drug for basal cell carcinomas (BCCs) deemed unsuitable for surgical resection or radiotherapy. Release of this drug was fast-tracked for January 2012 due to…
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Dec 10
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Incorrect Reconstitution of IncobotulinumtoxinA Leads to Loss of Neurotoxin

By No Comments
INTRODUCTION IncobotulinumtoxinA (INCO; Xeomin® in the United States, Canada / “botulinum toxin A free of complexing proteins» or Bocouture® in Europe and other parts of the world) is distributed by…
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Dec 10
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Efficacy and Safety of Ingenol Mebutate 0.015% Gel After Cryosurgery of Actinic Keratosis: 12-Month Results

By No Comments
INTRODUCTIONActinic keratosis (AK) is one of the most common dermatologic diagnoses that affects individuals ≥40 years (11–50% of the population in the United States and Australia,1 and 11–25% in Europe2,3).…
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Dec 10
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Successful Desensitization to Brentuximab Vedotin After Hypersensitivity Reaction

By No Comments
INTRODUCTION Monoclonal antibodies (mAb) are a growing area in the therapeutic armamentarium of numerous conditions including various cancers, autoimmune diseases, psoriasis, transplant rejection and cardiovascular diseases among others1. They allow…
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Dec 10
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Leuprolide Acetate-Induced Generalized Papular Eruption

By No Comments
INTRODUCTIONLeuprolide acetate is a gonadotropin-releasing hormone agonist used in the treatment of hormone responsive cancers such as prostate cancer and breast cancer, in addition to gynecologic disorders like endometriosis or…
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Dec 10
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Rosacea Fulminans With Extrafacial Lesions in an Elderly Man: Successful Treatment With Subantimicrobial-Dose Doxycycline

By No Comments
INTRODUCTION Rosacea fulminans (RF) is a rare and severe form of rosacea characterized by the sudden eruption of coalescing papules and pustules, and large cystic nodules limited almost exclusively to…
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