A 51-year-old woman presented to our attention because of a rapidly growing and painful toenail lesion. The lesion had been present for a few weeks.The patient was affected by Philadelphia…

The recent article by Aly et al provided for highly stimulating and interesting reading.1 Elevated serum leptin in patients with psoriasis may contribute to the development and progression of a…

INTRODUCTIONSkin cancer is the most common form of cancer in the United States. According to the World Health Organization, the incidence of both nonmelanoma and melanoma skin cancers has increased…

INTRODUCTIONBasal cell carcinoma (BCC) is the most common malignancy in people of European descent.1,2 BCCs comprise approximately 80% of nonmelanoma skin cancers. In the United States, more than 2 million…

BACKGROUND Skin cancer is increasing at epidemic proportions in the United States. More than 3.5 million nonmelanoma skin cancers (NMSCs)1 are diagnosed in the United States annually, with basal cell…

INTRODUCTIONRepeated exposure to solar ultraviolet (UV) radiation causes human skin to age prematurely (photoaging).1,2 Photoaged skin is characterized by a variety of clinical, histologic, and biochemical features. Wrinkles, uneven pigmentation…

INTRODUCTION Acne vulgaris is a common, multifactorial disease characterized by 4 pathophysiologic processes: 1) presence and activity of bacteria, 2) inflammation, 3) excess sebum production, and 4) excess keratinization.1 Clinically,…

INTRODUCTION Psoriasis patients are often frustrated with the treatment they receive.1-3 The quality-of-life impact of psoriasis is comparable to that of other major medical diseases such as arthritis, hypertension, and…

INTRODUCTIONTaurine is one of the most abundant amino acids in physiological fluids and tissues including serum, leukocytes, brain, kidney, and liver. Taurine is a ubiquitous single amino acid that is…

INTRODUCTIONSecond intention healing (SIH) is safe, well tolerated, provides for tumor surveillance, and is a cost-effective option for the handling of defects resulting from Mohs micrographic surgery (MMS). Healing in…

INTRODUCTION There is an increased frequency of disorders characterized by hyperpigmentation in darker racial ethnic groups (Fitzpatrick skin phototypes III-VI), and the treatment of hyperpigmentation in these patients has remained…

INTRODUCTION The incidence of nonmelanoma skin cancer (NMSC) has been reported to be increasing rapidly over the past few decades, with an estimated 2 million cases diagnosed annually.1-3 Composed largely…