Men also have larger facial pores and produce more sebum
than women. Caucasian men have an average of 3 μg of sebum
per square centimeter of skin surface, while Caucasian
women have 0.7 μg/cm2.42,43 Sebum helps waterproof and
lubricate the skin, and maintains flexibility of the stratum
corneum. Men usually find excess sebum undesirable, as it
is associated with pore enlargement, greasy-appearing skin
and acne.43
CLINICAL IMPLICATIONS
In 2014, the two most common cosmetic procedures performed
in men were injections of botulinum toxin type A (BTX-A) and
dermal fillers.1 Successful use of these injectable agents requires
a balancing act between masculinizing and feminizing the face,
as overuse or misplaced agents may result in poor cosmetic outcomes.
The presence of larger facial muscles in men requires higher
doses of BTX-A to achieve the same cosmetic effects observed
in women. A prospective, double-blind, randomized study by
Carruthers and Carruthers showed that the glabellar region in
men should be treated with at least 40 units of BTX-A, which
is twice the standard dose given to women.44 When treating
forehead rhytides in men, the medial and lateral frontalis
should be equally treated to avoid creating an eyebrow arch
(“Mephisto signâ€), which is feminizing when present in a male
patient. Crow’s feet in men usually have an inferior fanning
pattern due to the relative increased size of the zygomaticus