Individual Article: A Novel 3-Step Over-the-Counter Eczema Regimen Improves Eczema Severity, Itch, and Life Quality: Randomized Study

October 2023 | Volume 22 | Issue 10 | SF388641s21 | Copyright © October 2023


Published online September 30, 2023

Kristi Hawley DO FAADa, Peter Lio MDb, Thu Nguyen PhDc, Aamir Qureshi MDc, Christine Emesiani PharmDc, Matthew Meckfessel PhDc

aThe Derm Institute of West Michigan; Michigan State University College of Osteopathic Medicine, Petoskey, MI 
bMedical Dermatology Associates of Chicago, Chicago, IL 
cGalderma Laboratories, L.P., Dallas, TX

Figure 3 shows skin improvement in patient photos from individuals across a range of ages and a diverse panel. As can be appreciated in the photo of a young African American patient, there is dryness/scaling and an ashen gray look at the initiation of treatment and smoother, more hydrated looking skin at week 12. In the White patient, who was lost to follow up after week 8, a marked improvement in erythema and rash can be seen throughout the study. Similarly, improvements in rash, pigmentation, and overall appearance can be appreciated in the Asian patient.

The skincare regimen was also associated with a positive impact on QoL (P<0.05 for reduction at week 12 vs baseline), with clinically relevant reductions (Figure 4). As shown, this was true for both children and adults.

Analysis of the self-assessment questionnaire showed that a significantly greater proportion of participants selected favorable responses vs those with unfavorable responses on almost all questions at weeks 4 and 12 and to all at week 8. For example, at