characteristics are shown in Table 1. Approximately two-thirds of subjects were adults (29 aged 18 or older) with the remaining 10 subjects aged 12 to 17.
Efficacy
The skincare regimen achieved a significant improvement in itch throughout the study, as was reflected in the reduction of baseline mean POEM scores from 9.7 to 5.3 at week 12 and mean ItchyQuant score from 5.4 to 2.7 at week 12 (Figure 1, P<0.05 for both). The regimen also significantly improved mean EASI scores and reduced flares (Figure 2, P<0.05 for both). For the individual EASI parameters, there was a statistically significant improvement in erythema scores on the lower limbs at weeks 8 and 12; improvement of edema, induration, and papulation on the upper limbs at weeks 4, 8, and 12 and on the lower limbs at weeks 4 and 12; improvement of excoriation on upper limbs at all study visits, and less lichenification on upper limbs at week 12 (P<0.05 for all vs baseline).
