Efficacy of a Skin Condition-Adapted Solution for Xerosis and Itch Relief Associated With Aging

November 2016 | Volume 15 | Issue 11 | Supplement Individual Articles | 91 | Copyright © November 2016

Ramsin Joseph Yadgar BS,a and Adam J. Friedman MDa,b

aThe George Washington University, School of Medicine and Health Sciences,Washington, DC bDepartment of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY

use of the diffractive lens array alone or with the flat optic can be used successfully to treat unwanted pigmentation associated with photo damage in Asians.Apart from fractionated laser delivery, Fractional Pico Toning creates a novel injury based on the theory of laser-Induced Optical Breakdown (LIOB) for skin revitalization recently characterized by Tanghetti.23 Using picosecond alexandrite laser pulses intensified through a diffractive lens array, LIOB is created within the epidermis which results in a localized intra-epidermal injury where the surrounding epidermal cells remain intact. LIOB subsequently triggers a healing process and collagen remodeling to aid in the resurfacing process, potentially responsible for the continuous improvement of skin texture and fine wrinkles in our subjects over time.Secondly, after the creation of an LIOB a laser could potentially generate a pressure wave or shockwave which induces cellular changes that may ultimately result in the production of new collagen, mucin and elastic tissue. The high energy peaks of Fractional Pico Toning may also contribute to the photomechanical effect that is postulated. Both of these speculated mechanisms do not result in significant thermal damage. The preservation of the epidermis with this type of localized injury appears to lead to rejuvenation without a significant risk of dyspigmentation or prolonged downtime.The present study is limited by its small sample size and a relatively short follow up. Future exploration may involve a larger sample size and direct comparisons with other non-ablative modalities, such as QSNYL toning and intense pulsed light. Using fixed spot-sizes and low fluences, the non-fractional flat optic mode of Pico Toning may also be worth investigating for its potential tightening and lightening ability.


No conflict of interest was reported.


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Tong Lin MD PhD ddlin@hotmail.com