Evaluation of Efficacy
After four treatments, significant improvement in photoaging was observed at two-month follow up on the treated side of the face (Figures 1 and 2) compared to the control side (Figure 3), with GPS score decrease from 2.67 to 1.44 (P=0.005; Table 1). More significant improvement in wrinkles (Figure 4) was observed than that in pigmentation (Figure 5), with the APS score decrease from 2.78 to 1.89 (P=0.005). Treatment results improved gradually throughout the treatment regimen and achieved even better improvement at two-month follow up (Table 2). Furthermore, skin tightening was perceived in all subjects, and nasolabial folds improved in 60% of the subjects on the treated side of face.
Evaluation of Treatment-Associated Complications
Pain was the major treatment associated complication during the treatment process and was quantified immediately