Cosmetic Benefits of Natural Ingredients

September 2014 | Volume 13 | Issue 9 | Original Article | 1021 | Copyright © September 2014

Whitney P. Bowe MDa and Silvina Pugliese MDb

aIcahn School of Medicine at Mount Sinai Medical Center, New York, NY
bLoma Linda University, Department of Dermatology, Loma Linda, CA


Whitney P. Bowe has served the advisory board, or has been a speaker or consultant for Allergan, Inc, Bayer, Galderma Laboratories LP, Johnson & Johnson Consumer Products Company, L'Oreal USA Inc, Onset Therapeutics now Valeant , and Proctor and Gamble Company. Silvina Pugliese has not disclosed any potential conflicts.


  1. Ferreira IC, Barros L, Abreu RM. Antioxidants in Wild Mushrooms. Curr Med Chem. 2009;16(12):1543-60.
  2. Wasser SP. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol. 2002;60(3): 258–74.
  3. Bowe WP. Cosmetic benefits of natural ingredients: Mushrooms, feverfew, tea, and wheat complex. J Drugs Dermatol. 2013;12(9 Suppl):s133-6.
  4. Yu HM, Wang BS, Huang SC, Duh PD. Comparison of protective effects between cultured Cordyceps militaris and natural Cordyceps sinensis against oxidative damage. J Agric Food Chem . 2006;54(8):3132-8.
  5. Xiao JH, Xiao DM, Chen DX, Xiao Y, Liang ZQ, Zhong JJ. Polysaccharides from the medicinal mushroom Cordyceps Taii show antioxidant and immunoenhancing activities in a D-Galactose-induced aging mouse model. Evid Based Complement Alternat Med . 2012:273435.
  6. Shin SW, Jung E, Kim S, Lee KE, Youm JK, Park D. Antagonist effects of veratric acid against UVB-induced cell damages. Molecules. 2013;18(5):5405-19.
  7. Fowler JF Jr, Woolery-Lloyd H, Waldorf H, Saini R. Innovations in natural ingredients and their use in skin care. J Drugs Dermatol . 2010;9(6 Suppl):S72-81.
  8. Rodriguez KJ, Wong HK, Oddos T, Southall M, Frei B, Kaur S. A purified Feverfew extract protects from oxidative damage by inducing DNA repair in skin cells via a PI3-kinase-dependent Nrf2/ARE pathway. J Dermatol Sci . 2013;72(3):304-10.
  9. Martin K, Sur R, Liebel F, Tierney N, Lyte P, Garay M, Oddos T, Anthonavage M, Shapiro S, Southall M. Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression. Arch Dermatol Res . 2008;300(2):69-80.
  10. Nebus J, et al. Poster presented at: 63rd Annual Meeting of the American Academy of Dermatology; February 18-22, 2005; New Orleans, LA.
  11. Hong YH, Jung EY, Shin KS, Yu KW, Chang UJ, Suh HJ. Tannase-converted green tea catechins and their anti-wrinkle activity in humans. J Cosmet Dermatol . 2013;12(2):137-43.
  12. Mahmood T, Akhtar N. Combined topical application of lotus and green tea improves facial skin surface parameters.Rejuvenation Res . 2013;16(2):91-7.
  13. Kolbe L, Immeyer J, Batzer J, Wensorra U, tom Dieck K, Mundt C, Wolber R, Stäb F, Schönrock U, Ceilley RI, Wenck H. Anti-inflammatory efficacy of Licochalcone A: correlation of clinical potency and in vitro effects. Arch Dermatol Res . 2006;298(1):23-30.
  14. Ichihashi M, Ahmed NU, Budiyanto A, Wu A, Bito T, Ueda M, Osawa T. Preventive effect of antioxidant on ultraviolet-induced skin cancer in mice. J Dermatol Sci . 2000;23 Suppl 1:S45-50.
  15. Osborne R, Hakozaki T, Laughlin T, Finlay DR. Application of genomics to breakthroughs in the cosmetic treatment of skin ageing and discoloration. Br J Dermatol. 2012;166 Suppl 2:16-9.
  16. Baumann LS. Less-known botanical cosmeceuticals. Dermatol Ther . 2007;20(5):330-42.
  17. Mamalis A, Nguyen DH, Brody N, Jagdeo J. The active natural anti-oxidant properties of chamomile, milk thistle, and halophilic bacterial components in human skin in vitro. J Drugs Dermatol . 2013;12(7):780-4.
  18. Aburjai T, Natsheh FM. Plants used in cosmetics. Phytother Res . 2003;17(9):987-1000.
  19. Chen CY, Milbury PE, Collins FW, Blumberg JB. Avenanthramides are bioavailable and have antioxidant activity in humans after acute consumption of an enriched mixture from oats. J Nutr . 2007;137(6):1375-82.
  20. Criquet M, Roure R, Dayan L, Nollent V, Bertin C. Safety and efficacy of personal care products containing colloidal oatmeal. Clin Cosmet Investig Dermatol . 2012;5:183-93.
  21. Ulbricht C, Brigham A, Burke D, Costa D, Giese N, Iovin R, Grimes Serrano JM, Tanguay-Colucci S, Weissner W, Windsor R. An evidence-based systematic review of acai (Euterpe oleracea) by the Natural Standard Research Collaboration. J Diet Suppl . 2012;9(2):128-47.
  22. Del Pozo-Insfran D, Percival SS, Talcott ST. Açai (Euterpe oleracea Mart.) poly-phenolics in their glycoside and aglycone forms induce apoptosis of HL-60 leukemia cells. J Agric Food Chem . 2006;54(4):1222-9.
  23. Sparavigna A. High total antioxidant capacity products added to diet. www. identifier: NCT00975728 accessed April 2011.
  24. Huang CC, Hsu BY, Wu NL, Tsui WH, Lin TJ, Su CC, Hung CF. Anti-photoaging effects of soy isoflavone extract (aglycone and acetylglucoside form) from soybean cake. Int J Mol Sci . 2010;11(12):4782-95.
  25. Wallo W, Nebus J, Leyden JJ. Efficacy of a soy moisturizer in photoaging: a double-blind, vehicle-controlled, 12-week study. J Drugs Dermatol . 2007;6(9):917-22.
  26. Lethaby A, Marjoribanks J, Kronenberg F, Roberts H, Eden J, Brown J. Phytoestrogens for menopausal vasomotor symptoms. Cochrane Database Syst Rev . 2013.
  27. Farris P. Idebenone, green tea, and Coffeeberry extract: new and innovative antioxidants. Dermatol Ther . 2007;20(5):322-9.


Whitney P. Bowe