Original Article

Skin Barrier Health: Regulation and Repair of the Stratum Corneum and the Role of Over-the-Counter Skin Care

Lee, T. et al.

The epidermis functions as a physical barrier that separates the inner body from the outside environment. The outermost layer of the epidermis, the stratum corneum, plays a key role in maintaining this barrier. There are numerous biochemical changes .......

Read more

Original Article

Cosmetic Use of AbobotulinumtoxinA in Men: Considerations Regarding Anatomical Differences and Product Characteristics

Bloom, J. et al.

The proportion of men seeking facial rejuvenation with botulinum neurotoxin type A (BoNTA) products is increasing. The number of male patients treated in the 5-year period between 2009 and 2014 grew by 25%. There is little clinical data supporting ge.......

Read more

Original Article

Patient Reported Outcomes from HIV Facial Lipoatrophy Treatment With a Volumizing Hyaluronic Acid Filler: A Prospective, Open-Label, Phase I and II Study

Ho, D. et al.

BACKGROUND: Human immunodeficiency virus (HIV) facial lipoatrophy (FLA) is associated with the use of highly active antiretroviral therapy (HAART) and HIV disease. HIV FLA is primarily characterized by midface (cheeks and temples) volume loss, result.......

Read more

Original Article

Microneedling Prior to Levulan PDT for the Treatment of Actinic Keratoses: A Split-Face, Blinded Trial

Spencer, J. et al.

INTRODUCTION: Photodynamic Therapy (PDT) with topical Levulan is an approved and efficacious method for treating actinic keratoses. This therapy depends on the ability of the Levulan (delta amino levulinic acid) to penetrate the stratum corneum and e.......

Read more

Original Article

Lip Injection Techniques Using Small-Particle Hyaluronic Acid Dermal Filler

Chiu, A. et al.

The shape and fullness of the lips have a significant role in facial aesthetics and outward appearance. The corrective needs of a patient can range from a subtle enhancement to a complete recontouring including correction of perioral rhytides. A comp.......

Read more

Original Article

Efficacy and Safety of IncobotulinumtoxinA in Asian Subjects: A Pooled Analysis of Clinical Trials in the Treatment of Glabellar Frown Lines

Seo, K. et al.

BACKGROUND: Owing to differences in facial anatomy and cultural beauty ideals, dose adaptations are often necessary when administering botulinum toxin type A to Asians and non-Asians. Objective: To assess potential differences in the efficacy and sa.......

Read more

Original Article

Visual, Ultrasonographic, and Microscopic Study on Hyaluronic Acid-Based Gel

Micheels, P. et al.

BACKGROUND: Hyaluronic acid (HA) fillers are commonly used for enhancement of lips, and for softening fine lines and correcting skin depressions. Objective: This study sought to investigate whether the Vycross technology used for V.......

Read more

Original Article

An Open Label Clinical Trial of a Peptide Treatment Serum and Supporting Regimen Designed to Improve the Appearance of Aging Facial Skin

Draelos, Z. et al.

A 14-week single-center clinical usage study was conducted to test the efficacy of a peptide treatment serum and supporting skincare regimen in 29 women with mild to moderately photodamaged facial skin. The peptide treatment serum contained gamma-ami.......

Read more

Original Article

Rheological Properties of Calcium Hydroxylapatite With Integral Lidocaine

Meland, M. et al.

BACKGROUND: Calcium hydroxylapatite with integral lidocaine, CaHA (+), received FDA approval in 2015 and CE mark approval in 2016. This formulation has been associated with significant pain reduction compared to CaHA. In a previous rheometry study, C.......

Read more

Original Article

Econazole Nitrate Foam 1% Improves the Itch of Tinea Pedis

Fleischer, A. et al.

Econazole nitrate topical foam, 1%, is indicated for the treatment of interdigital tinea pedis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum in patients 12 years of age and older. The sympt.......

Read more

Original Article

Efinaconazole 10% and Tavaborole 5% Penetrate Across Poly-ureaurethane 16%: Results of In Vitro Release Testing and Clinical Implications of Onychodystrophy in Onychomycosis

Adigun, C. et al.

BACKGROUND: Poly-ureaurethane has been previously described for the management of dry, brittle, and in general, dystrophic nails. The polymer yields a waterproof, breathable barrier to protect the nail plate and prevent further damage to the nail, .......

Read more

Original Article

Online Survey of US Dermatologists’ Sunscreen Opinions: Perceptions, Recommendation Factors, and Self-Usage

Farberg, A. et al.

The American Academy of Dermatology and dermatologists’ themselves, have recommended public education and patient counseling regarding sunscreen. The purpose of this study was to determine US dermatologists’ actual sunscreen perceptions as well as th.......

Read more