Case Reports
Ruxolitinib 1.5% Topical Cream for the Treatment of Pediatric Alopecia Areata
May 2024 | Volume 23 | Issue 5 | Case Reports | 378 | Copyright © May 2024
Alopecia areata (AA) is a common autoimmune disorder. Although its pathogenesis is not fully understood, AA involves CD8 T cell-mediated destruction of the hair follicle. Several treatment option...
Read MoreMetastatic Merkel Cell Carcinoma After Simultaneous Pancreas-Kidney Transplantation: Fatal Outcomes
May 2024 | Volume 23 | Issue 5 | Case Reports | 376 | Copyright © May 2024
Merkel cell carcinoma (MCC) is a rare, highly aggressive cutaneous malignancy. Immunosuppression increases the risk of MCC and is associated with poor prognosis. Organ transplant recipients (OTR)...
Read MoreA Pearl for Pretibial and Forearm Repair Following Mohs Micrographic Surgery
May 2024 | Volume 23 | Issue 5 | Case Reports | 380 | Copyright © May 2024
Wound repair of the pretibial and forearm regions presents a challenge during dermatologic surgery as these areas are under significant tension and exhibit increased skin fragility. Various metho...
Read MoreHydroxychloroquine-Induced Nonthrombocytopenic Purpura: A Case Series
May 2024 | Volume 23 | Issue 5 | Case Reports | e124 | Copyright © May 2024
Hydroxychloroquine (HCQ) is a disease-modifying anti-rheumatic medication for the treatment of various autoimmune conditions. A rare side effect of HCQ is thrombotic thrombocytopenic purpura (TTP). We...
Read MoreThe Koebner Phenomenon in Bullous Pemphigoid
April 2024 | Volume 23 | Issue 4 | Case Reports | e100 | Copyright © April 2024
Cutaneous Squamous Cell Carcinoma In Situ on a Fingernail Treated With HPV Vaccine
April 2024 | Volume 23 | Issue 4 | Case Reports | 275 | Copyright © April 2024
Oral Lichen Planus Successfully Treated With Upadacitinib
April 2024 | Volume 23 | Issue 4 | Case Reports | e104 | Copyright © April 2024
With the rise of Janus kinase (JAK) and Signal Transducer and Activator of Transcription (STAT) inhibitor use in dermatologic conditions, there has been increasing hope in treating extensive and ...
Read MoreMitogen-Activated Protein Kinase Inhibitor-Induced Inflammatory Alopecia in Woman With Ovarian Cancer
April 2024 | Volume 23 | Issue 4 | Case Reports | e102 | Copyright © April 2024
Inflammatory alopecia is an increasingly reported side effect of targeted cancer therapies. Here we report one case of inflammatory alopecia secondary to mitogen-activated protein kinase kinase (...
Read MorePemphigus Vulgaris Successfully Treated With Bromocriptine
March 2024 | Volume 23 | Issue 3 | Case Reports | e83 | Copyright © March 2024
Pemphigus vulgaris (PV) is an autoimmune blistering skin condition primarily treated with immunosuppressive agents. We describe a case of PV successfully treated with nonconventional treatment, b...
Read MoreNovel Clinical Applications of Topical Ruxolitinib: A Case Series
March 2024 | Volume 23 | Issue 3 | Case Reports | 188 | Copyright © March 2024
Topical ruxolitinib, a potent Janus kinase (JAK) inhibitor, has shown significant efficacy in treating inflammatory skin conditions. While its use has already been established in atopic dermatiti...
Read MoreUrticaria Pigmentosa Without Pruritus
March 2024 | Volume 23 | Issue 3 | Case Reports | e81 | Copyright © March 2024
Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastoc...
Read MoreFirst Use of Combination Oral Deucravacitinib With Tapinarof Cream for Treatment of Severe Plaque Psoriasis
March 2024 | Volume 23 | Issue 3 | Case Reports | 192 | Copyright © March 2024
Plaque psoriasis is a chronic, immune-mediated, cutaneous, and systemic inflammatory dermatosis. Its pathogenesis involves the dysregulation of the interleukin (IL)-23/IL-17 signaling pathway. Th...
Read MorePsoriasis and Palmoplantar Pustulosis Following Pembrolizumab Therapy Successfully Treated With Topical Tapinarof Cream 1%
February 2024 | Volume 23 | Issue 2 | Case Reports | 103 | Copyright © February 2024
Atypical Dyschromia in Skin of Color
February 2024 | Volume 23 | Issue 2 | Case Reports | 100 | Copyright © February 2024
Dyschromia is a concern for many patients, especially persons of color. Postinflammatory hypopigmentation and depigmentation can affect all skin types; however, it is more apparent in those with ...
Read MoreAtopic Dermatitis as a Paradoxical Reaction to Secukinumab in a Patient With Plaque Psoriasis
February 2024 | Volume 23 | Issue 2 | Case Reports | 97 | Copyright © February 2024
Paradoxical reactions to biologic agents used in the treatment of psoriasis are rare but have been reported with tumor necrosis factor (TNF) blockers and, more recently, with interleukin (IL)-17A...
Read MoreSarecycline as a Potential Treatment for Steroid-Induced Rosacea/Perioral Dermatitis: A Case Report
February 2024 | Volume 23 | Issue 2 | Case Reports | e55 | Copyright © February 2024
Neoadjuvant PD-1 Inhibitors: A Tale of Two Cases
February 2024 | Volume 23 | Issue 2 | Case Reports | e57 | Copyright © February 2024
Treatment responses for locally advanced cutaneous squamous cell carcinoma (cSCC) and Merkel cell carcinoma (MCC) are often short lived and are marred with recurrences. The introduction of adjuva...
Read MoreA Case Series of TNF Inhibitor-Induced Psoriasis Successfully Treated With Upadacitinib
February 2024 | Volume 23 | Issue 2 | Case Reports | e60 | Copyright © February 2024
Tumor necrosis factor-alpha inhibitors (TNF-i) are commonly used to treat immune-mediated diseases such as psoriasis, psoriatic arthritis (PsA), inflammatory bowel disease (IBD), spondyloarthriti...
Read MorePost-Hyaluronic Acid Filler Reaction Treated With Abrocitinib: A Case Report
January 2024 | Volume 23 | Issue 1 | Case Reports | 1355 | Copyright © January 2024
Post-hyaluronic acid filler nodules are uncommon, unpredictable complications that present a challenge to clinical therapy. We report a case of a female in her fifties who developed edema and nod...
Read MoreA Case Series of Patients With Eczematous Eruptions Following IL-17 Inhibitor Treatment for Psoriasis Vulgaris
December 2023 | Volume 22 | Issue 12 | Case Reports | 1225 | Copyright © December 2023
Psoriasis vulgaris and eczema are characterized by an imbalance in the Th1 and Th2 immune response and distinct cytokine profiles, where Th1 is more prominent in psoriasis and Th2 is more promine...
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