Case Reports
Nonresponse and Progression of Diffuse Keloids to Dupilumab Therapy
February 2022 | Volume 21 | Issue 2 | Case Reports | 6252 | Copyright © February 2022
Th2 cytokines, including IL-4 and IL-13, have been shown to increase TGFβ, promoting fibrosis. A recent study showed keloid improvement in one patient after administration of Dupilumab, an IL-4 r...
Read MoreIntralesional Bleomycin Combined With Cryotherapy in the Treatment of Recalcitrant Verruca Vulgaris
February 2022 | Volume 21 | Issue 2 | Case Reports | 6424 | Copyright © February 2022
Verruca vulgaris is a common cutaneous manifestation of Human Papillomavirus (HPV) infection that presents as hyperkeratotic, cauliflower-like papules with central black petechiae. These lesions may b...
Read MoreTreatment of Hyperpigmented Discoid Lupus Erythematosus With Jessner's Peel: A Case Report
January 2022 | Volume 21 | Issue 1 | Case Reports | 92 | Copyright © January 2022
Discoid lupus erythematosus (DLE) is the most common type of chronic cutaneous lupus erythematosus and is categorized by well-demarcated, often hyper or hypopigmented macules or papules that gradually...
Read MoreSevere Ulcerative Perniosis Treated With Abobotulium Toxin
December 2021 | Volume 20 | Issue 12 | Case Reports | 1350 | Copyright © December 2021
Perniosis (also known as pernio or chilblains), is a condition characterized by the development of pruritic, painful erythrocyanotic skin lesions induced by exposure to cold temperatures.2 When pernio...
Read MoreProliferating Pilar Tumor: Two Cases and a Review of the Literature
December 2021 | Volume 20 | Issue 12 | Case Reports | 1346 | Copyright © December 2021
Trichilemmal cysts (TCs) are the most common cystic lesions arising on the scalp and up to 2% give rise to a proliferating trichilemmal tumor (PTT). A rare subset of PTTs are termed malignant due to t...
Read MoreChromate-Induced Allergic Contact Dermatitis Treated With Dupilumab
December 2021 | Volume 20 | Issue 12 | Case Reports | 1340 | Copyright © December 2021
Chromate causes persistent, difficult to treat irritant and allergic contact dermatitis in cement-handling occupational workers. When therapeutics such as topical corticosteroids, topical calcineurin ...
Read MoreDelayed Metastatic Polypoid Nodular Melanoma Diagnosis During COVID-19 Pandemic, Successful Treatment With Surgery and Nivolumab
December 2021 | Volume 20 | Issue 12 | Case Reports | 1343 | Copyright © December 2021
Patients with polypoid (pedunculated) melanoma have the poorest 5-year survival rate compared with all other variants of nodular melanoma, presenting with increased thickness, incidence of metastasis,...
Read MoreSuccessful Treatment of Brunsting-Perry Cicatricial Pemphigoid With Dupilumab
October 2021 | Volume 20 | Issue 10 | Case Reports | 1113 | Copyright © October 2021
Brunsting-Perry is a rare variant of cicatricial pemphigoid, characterized by subepidermal bullae localized to the head and neck. Currently, treatment relies on non-specific immunosuppression, which i...
Read MoreSuccessful Use of Tildrakizumab for Treatment of Palmoplantar Pustulosis: A Case Report
October 2021 | Volume 20 | Issue 10 | Case Reports | 1117 | Copyright © October 2021
Palmoplantar pustulosis (PPP) is a rare, recurrent skin disorder that presents a major challenge to clinical therapy. We report a case of a 69-year-old woman with a 20-year history of psoriasis with s...
Read MoreAn Extensive Presentation of Cutaneous Angiosarcoma
August 2021 | Volume 20 | Issue 8 | Case Reports | 895 | Copyright © August 2021
In this report, the case of a 58-year-old male with extensive, rapidly growing cutaneous angiosarcoma is described. Though involvement of the scalp is common in cutaneous angiosarcoma, the extent of c...
Read MoreHerpes Zoster Following COVID-19 Vaccination
August 2021 | Volume 20 | Issue 8 | Case Reports | 898 | Copyright © August 2021
Vaccination is an important intervention in preventing the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Messenger RNA (mRNA) vaccines from Pfizer™ and Moderna™ a...
Read MoreCombining Panitumumab With Anti-PD-1 Antibody in Cutaneous Squamous Cell Carcinoma of the Head and Neck After Inadequate Response to Anti-PD-1 Antibody Alone
August 2021 | Volume 20 | Issue 8 | Case Reports | 901 | Copyright © August 2021
Anti-epidermal growth factor receptor (EGFR) antibodies and anti-programmed cell death 1 protein (PD-1) antibodies have been used separately to treat metastatic cutaneous squamous cell carcinoma (cSCC...
Read MorePediatric Lichen Planopilaris Treated With Pioglitazone: A Case Study and Literature Review
July 2021 | Volume 20 | Issue 7 | Case Reports | 779 | Copyright © July 2021
Importance: Pediatric lichen planopilaris (LPP) is a clinical variant of lichen planus (LP) that can lead to scarring hair loss without prompt intervention. While various therapies ex...
Read MoreTreatment of Rhinophyma With Fractional CO2 Laser Resurfacing in a Woman of Color: Case Report and Review of the Literature
July 2021 | Volume 20 | Issue 7 | Case Reports | 772 | Copyright © July 2021
Rhinophyma is a disfiguring disorder that is characterized by an erythematous, hypertrophied, and inflamed lower two-thirds of the nose. Widely accepted as the severe form of acne rosacea, rhinophyma ...
Read MoreTreatment Dissecting Cellulitis of the Scalp With Secukinumab
July 2021 | Volume 20 | Issue 7 | Case Reports | 776 | Copyright © July 2021
Dissecting cellulitis of the scalp (DCS), also known as perifolliculitis capitis abscedens and suffodiens, is a form of neutrophilic cicatricial alopecia leading to irreversible hair loss.1...
Read MoreHand Foot Skin Reaction Associated With Palbociclib
July 2021 | Volume 20 | Issue 7 | Case Reports | 783 | Copyright © July 2021
Palbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth fa...
Read MoreNovel Treatment of In-Transit Metastatic Melanoma With Shave Excision, Electrodesiccation and Curettage, and Topical Imiquimod 5% Cream
May 2021 | Volume 20 | Issue 5 | Case Reports | 555 | Copyright © May 2021
In-transit metastatic melanoma is classified as a regional intralymphatic metastasis of melanoma. Currently, there is no standardized regimen used to treat in-transit metastatic melanoma, and therapy ...
Read MoreVismodegib as Eye-Sparing Neoadjuvant Treatment for Locally Advanced Periocular Basal Cell Carcinoma
May 2021 | Volume 20 | Issue 5 | Case Reports | 552 | Copyright © May 2021
Locally-advanced periocular basal cell carcinoma (BCC) pose many therapeutic challenges due to the need to preserve functionality and cosmesis of the orbit and periocular area. Surgical excision and s...
Read MoreA Case of Cutaneous Blastic Plasmacytoid Dendritic Cell Neoplasm Treated With a Bcl-2 Inhibitor
May 2021 | Volume 20 | Issue 5 | Case Reports | 550 | Copyright © May 2021
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive primary cutaneous lymphoma characterized by transformed plasmacytoid dendritic cells that overexpress interleukin-3 recept...
Read MoreTwo Cases of Recalcitrant Dyshidrotic Eczema Treated With Dupilumab
May 2021 | Volume 20 | Issue 5 | Features | 558 | Copyright © May 2021
Dyshidrotic eczema, also known as dyshidrosis or pompholyx when involving larger bullae, is a chronic, relapsing palmoplantar...
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