Current Issue
March 2021 | Volume 20 | Issue 3
Editorials
Clinical Trial of High-Dose Pegylated-Interferon-Alfa-2b Combined With Phototherapy in Advanced Stage Mycosis Fungoides
The combination of Interferon-α-2b (IFN-α-2b) and phototherapy is highly effective in treating mycosis fungoides (MF) but side effects often lead to discontinuation of therapy.1...
Read MoreThe Use of Tranexamic Acid to Prevent and Treat Post-Inflammatory Hyperpigmentation
The risk of post-inflammatory hyperpigmentation (PIH) in patients undergoing dermatologic procedures is well known. It is especially common after laser procedures and chemical peels but can be seen wi...
Read MoreCoronavirus Vaccination Adverse Reactions and the Role of the Dermatologist
Original Articles
Tolerability and Efficacy of Clindamycin/Tretinoin versus Adapalene/Benzoyl Peroxide in the Treatment of Acne Vulgaris
Acne vulgaris is the most common dermatological disorder worldwide, causing significant physical and psychological morbidity. Topical combination therapy has shown superior efficacy compared to monoth...
Read MoreCharacteristics of Superficial Basal Cell Carcinomas Containing More Aggressive Subtypes on Final Histopathologic Diagnosis
Background: The prognosis and treatment of basal cell carcinoma (BCC) are largely dependent on tumor subtype, which is typically determined by punch or shave biopsy. Data regarding concordance between...
Read MoreA Non-Surgical and Cost-Effective Treatment Approach Employing Topical Imiquimod, 5-Fluorouracil, and Tretinoin for Primary Non-Melanoma Skin Cancers
Background: Minimally invasive alternative approaches to treat non-melanoma skin cancers remain limited and unproven.
Objective: We aim to assess the efficacy of varying combinations of anti-tum...
Read MoreHigh Volume Liposuction in Tumescence Anesthesia in Lipedema Patients: A Retrospective Analysis
Background: Lipedema is a chronic, progressive disease that occurs almost exclusively in women and leads to pathological, painful fat growths at the extremities. Only symptomatic therapy can be offere...
Read MoreAfamelanotide: An Orphan Drug with Potential for Broad Dermatologic Applications
Afamelanotide (SCENESSE®) is a synthetic analogue of α‐melanocyte-stimulating hormone that is FDA-approved to increase pain-free sunlight exposure in adult patients with erythropoietic pro...
Read MoreAdding Combined Oral Contraceptives or Metformin to Laser Treatment in Polycystic Ovarian Syndrome Hirsute Patients
Background: Hirsutism is estimated to affect 10% to 20% of females, provoking significant psychological damage and social embarrassment. Polycystic ovary syndrome is a major cause of hirsutism.
...
Read MoreNovel Facial Treatment Regimen Improves Aging Skin Appearance
Background: Skin care regimens with multiple active ingredients offer a multimodal approach to anti-aging treatments.
Objective: The objective of this research was to investigate the efficacy of...
Read MoreA Clinical Study Evaluating the Efficacy of Topical Bakuchiol (UP256) Cream on Facial Acne
Acne vulgaris is a common skin disease that manifests clinically as comedones, papules, nodules, and cysts. In this single center, open-label pilot study (ISRCTN13992386), we aimed to evaluate the eff...
Read MoreMohs Micrographic Surgery for Genital Skin Cancer: A Review of Cases and Reconstructive Techniques
As the incidence of non-melanoma skin cancer (NMSC) increases in the United States, one area of particular concern is NMSC arising on the genitalia. In the past, most genital skin tumors have been tre...
Read MoreOnce-Daily Halobetasol Propionate 0.01% Lotion for Moderate-to-Severe Plaque Psoriasis: Phase 3 Analysis of Hispanic Participants
Background: Psoriasis is a chronic, inflammatory disease that may differ in prevalence and clinical presentation among patients from various racial and ethnic groups. Two phase 3 studies demonstrated ...
Read MoreMethotrexate Monitoring in Dermatology— A Retrospective Cohort Study
Background and Objectives: There are currently no evidence-based recommendations to guide lab monitoring in the first 90 days of methotrexate treatment. The purpose of this study was to determine whet...
Read MoreOver the Counter Products for Acne Treatment and Maintenance in Latin America: A Review of Current Clinical Practice
Background: The prevalence and clinical presentation of acne vulgaris in Latin America are comparable to that in Europe and the United States. This review aims at insight into the role of Over the Cou...
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Features
Topical Imiquimod for Lentigo Maligna: Survival Analysis of 103 Cases With 17 Years Follow-up
Topical imiquimod 5% cream has been investigated as off-label primary or adjuvant treatment for melanoma in situ, lentigo maligna type (LM). Herein, we present the largest known case series of lentigo...
Read MoreAn Updated Therapeutic Strategy for Chronic Idiopathic Urticaria
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