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"Clean," "Natural," "Cruelty-Free": Why Your Patients Are Asking—and What You Need to Know With the rise of “clean beauty,” more patients are coming to dermatology visits with questions about the…

Time for a Global Standard? Rethinking Topical Corticosteroid Classification Topical corticosteroids (TCS) are a mainstay in dermatology, used to treat a wide range of skin conditions. While effective and generally…

Photodynamic Therapy for Actinic Keratosis: Can We Make It Painless? Actinic keratosis (AK), a common result of sun damage, can be a warning sign for squamous cell carcinoma. With skin…

What Happens After Isotretinoin? New Insights Into Post-Treatment Acne Care Isotretinoin remains the gold standard for treating severe acne, but relapse after treatment is common, affecting 20 to 60% of…

The Hidden Role of C. acnes in Dandruff: Beyond the Flakes Dandruff affects nearly 50% of the global population, yet its exact causes remain under ongoing investigation. While most clinicians…

Isotretinoin Dosing in Adolescents: Does Weight Change Matter? Isotretinoin remains the gold standard for treating severe nodulocystic acne, with cumulative dosing of 120-150 mg/kg shown to balance safety and efficacy. Higher…

Upadacitinib may provide additional health benefits, including reducing the risk of major adverse cardiovascular events (MACE) and venous thromboembolism (VTE). That’s according to a May Journal of Drugs in Dermatology…

Faster Relief for Seborrheic Dermatitis? A Case for Topical Roflumilast Seborrheic dermatitis is a chronic inflammatory skin condition that often frustrates patients and clinicians alike, especially during flare-ups. While topical corticosteroids…

By Allison Sit A new American Academy of Dermatology (AAD) survey shows American adults may not fully understand the benefits of sunscreen. The survey of 1,000 adults found nearly one…

What Skin Toxicities May Signal in Melanoma Patients on Immunotherapy Cutaneous immune-related adverse events (irCAEs) are among the most common side effects seen in patients receiving immune checkpoint inhibitors (ICIs)…

Test Your Knowledge! Join Dr. Alexis Carrington, Chief Dermatology Resident at George Washington University, to help understand dermatologic conditions across all skin tones. Decoding Derm: What’s the Diagnosis is a…

Painless™ PDT vs. Conventional PDT: A Quick Look at Patient Comfort in AK Treatment Actinic keratosis (AK) is one of the most common conditions treated by dermatologists, and photodynamic therapy…

Melanoma Education on Instagram: What’s Missing—Especially for Skin of Color As melanoma rates rise, with a projected 7.3% increase in new cases and 3.8% rise in mortality in 2024, the…

What to Expect When Treating SCC In Situ with Mohs Surgery While squamous cell carcinoma in situ (SCCIS) is typically considered a low-risk skin cancer, treatment decisions, especially around surgical…

EMPSGC: Why Mohs Might Be the Better Choice Endocrine Mucin Producing Sweat Gland Carcinoma (EMPSGC) is rare, low-grade, and slow-growing—but it’s not without risk. Though uncommon, recurrence and even distant…

This webinar delves into the emerging field of dermatoporosis, a chronic skin fragility condition. Participants will explore the latest translational research that bridges basic science and clinical practice, enhancing our…

From the Vault As more patients turn to the internet for guidance on pregnancy-safe skincare, dermatologists are increasingly fielding questions about what’s safe to use during pregnancy. One JDD article,…

Could Proteasome Inhibitors Offer a New Option for Pressure Injuries? Pressure injuries, especially in the sacral area, are a frequent and frustrating challenge, particularly in elderly patients. Standard care focuses…

In acknowledgement of National Melonoma and Skin Cancer Awareness Month, we are rerunning this series of Decoding Derm. Join Dr. Alexis Carrington in Decoding Dermatology: What’s the Diagnosis, as she presents a…

Knowledge is Critical for Successful Outcomes: Current Landscape of Hyaluronic Acid Filler Use in the United States When a recent article of Allure recently explored the science behind “medical-grade”…

WATCH NOW: Racial and Ethnic Representation in Atopic Dermatitis Clinical Trials With content flying at us from every direction, it’s easy to miss what matters most. That’s why JDD Corner…

Melanoma Mortality Drops Where Dermatologists Are in High Supply: Read the Data New data shows a powerful link: the more dermatologists in your area, the lower your risk of dying…

Just put some salve on it" sounds so innocuous one could follow up with, "what could possibly go wrong?" Never ask that. Yes, our skin is our living breathing barrier…

Cylindrocarcinoma: Could Mohs Surgery Be the Clear-Cut Winner? Cylindrocarcinoma—a rare malignant offshoot of benign cylindromas—poses a surgical challenge due to its potential for recurrence and metastasis. While traditional excision has…

Explore JDDonline If you’re on the hunt for expert-led, handpicked resources on psoriasis, you’re in the right place. Whether you're brushing up on the latest treatment insights or looking for…

A Fern with Far-Reaching Potential: The Role of Polypodium Leucotomos Extract in Dermatology From photoaging to pigmentary disorders, Polypodium leucotomos extract (PLE)—a botanical with notable photoprotective and anti-inflammatory properties—has emerged…

Did you miss it? By 2044, people with skin of color (SOC) will make up the majority of the U.S. population—but dermatology still lags behind in addressing their unique needs.…

Acne Treatment Without the Dry-Out: Clascoterone Cream 1% Proves Gentle on the Skin Barrier Topical acne meds often come with an unfortunate side effect: dry, irritated skin that leaves patients…

Active ingredients play a critical role in the efficacy and safety of cosmeceuticals. Join Dr. Corey L. Hartman, as he shares information on a new cosmeceutical formulation. This presentation will…

April Issue Must-Read! Hidradenitis suppurativa (HS) isn’t just painful—it’s deeply isolating. And new data reveals why: the majority of people living with HS don’t feel heard, treated, or informed. In a…

Did you miss this #acneceuticals article from April’s issue? What if your acne routine could be smarter, more personalized—and actually stick? Say hello to the new acne algorithm that’s changing…

Beyond the Granuloma: Rethinking Treatment Strategies for Generalized Granuloma Annulare Long considered a therapeutic challenge, generalized granuloma annulare (GGA) continues to defy many conventional treatment approaches. While topical steroids may…

Explore JDDonline If you’re on the hunt for expert-led, handpicked resources on atopic dermatitis, you’re in the right place. Whether you're brushing up on the latest treatment insights or looking…

Rituximab in the Treatment of Epidermolysis Bullosa Acquisita: A Systematic Review of the Literature
Could Rituximab Be the Key to Managing Epidermolysis Bullosa Acquisita? Epidermolysis bullosa acquisita (EBA) is a rare and often debilitating autoimmune blistering disease that remains notoriously difficult to manage. While…

A Breakthrough Approach to Aging Skin: Can This Cream Combat Dermatoporosis? As skin ages, it becomes fragile, thin, and prone to bruising - a condition known as dermatoporosis, which is…

By Allison Sit Dermatologist Aimee Payne, MD, PhD, is part of the second cohort of investigators with the Chan Zuckerberg Biohub New York, a research institute that is focused on harnessing…

Are Atopic Dermatitis Clinical Trials Becoming More Inclusive? Atopic dermatitis (AD) affects over 31 million people in the U.S., disproportionately impacting racial and ethnic minorities who often experience greater disease…

Can a Botanical Serum Support Hair Growth? Hair thinning and loss can be frustrating, leaving many searching for effective, non-pharmaceutical solutions. A recent 6-month study explored the potential of REVIVV®, a…

Moisturizer and Microbiome: A New Approach to AD Management? Staphylococcus aureus colonization is linked to atopic dermatitis (AD), but could topical skincare help restore balance? A moisturizer containing colloidal oatmeal and…

Test Your Knowledge! Join Dr. Alexis Carrington, Chief Dermatology Resident at George Washington University, to help understand dermatologic conditions across all skin tones. Decoding Derm: What’s the Diagnosis is a…

GLP-1 Agonists and Skin Reactions: What Dermatologists Should Know GLP-1 agonists are widely used for diabetes and weight management, but how do they impact the skin? This study reviews cutaneous…

Dupilumab for Refractory Hailey-Hailey Disease Hailey-Hailey disease (HHD) is a challenging chronic skin disorder marked by painful blisters and erosions. Treatment can be difficult, with many patients experiencing recurrent flare-ups despite…

Could GLP-1 Agonists Offer a New Approach to Hidradenitis Suppurativa? Hidradenitis Suppurativa (HS) is a challenging inflammatory skin condition often linked to obesity and metabolic dysfunction. With GLP-1 agonists gaining attention…

Spotlight on Rosacea: Beyond the Redness This National Rosacea Month April marks National Rosacea Month, a timely reminder for dermatology professionals to sharpen their diagnostic lens beyond textbook erythema. While…

Listen Now! Dermatology is always evolving, and if you haven’t caught the latest "Ask the Investigator" podcast episodes, you're missing out on game-changing insights! Hosted by the always-engaging Dr. Adam…

Featured Podcast Life's an itch sometimes….am I right? Pruritus can pick apart the fabric of one's life as both a symptom of a primary skin disease or even as a…

Looking for images for your next lecture or presentation? We’ve got you covered! In dermatology, accurate diagnosis and treatment rely heavily on recognizing how conditions present across diverse skin tones.…

Featured Podcast Even in a world of exponentially expanding systemic options both on and off label, one fact remains: topical therapy is ALWAYS on the menu. With an unprecedented array…

Did you miss this March article? Generalized pustular psoriasis (GPP) is a serious and unpredictable skin condition with limited treatment options. The Effisayil 1 trial evaluated spesolimab, a monoclonal antibody…

Prioritizing Skincare in Cancer Treatment: A Latin American Initiative Cancer treatments often lead to skin-related side effects that impact quality of life and, in some cases, treatment adherence. The Latin…

AI-Powered Personalization for Hair Loss: A Promising Alternative? With up to 50% of women and 80% of men experiencing hair loss, many turn to generic over-the-counter solutions—often with disappointing results.…

Did You Miss It? Micronized isotretinoin is an established treatment for severe nodular acne, but can it be effectively dosed once daily instead of twice? A new pilot study explores…

Articles from the Archives Lichen planus pigmentosus (LPP) remains one of dermatology's most enigmatic conditions—often presenting insidiously, confounding diagnoses, and challenging treatment plans. Whether it appears as diffuse gray-brown patches…

Acneceuticals: A New Era in Acne Care? Pharmaceuticals and procedures have long been the backbone of acne treatment, but over-the-counter skincare is playing an increasingly recognized role. This new paper…

JDD's Must Watch Feature At JDDonline, we're always looking for new ways to bring valuable dermatology research to life. One of the most dynamic and engaging features we offer is…

JAK Inhibitors in Alopecia Areata: A Case for Persistence? Oral Janus kinase inhibitors (JAKi) have emerged as a promising treatment for severe alopecia areata, with FDA-approved options now available. But…

Listen Now! If you've been snoozing on the latest JDD "Ask the Investigator" podcast episodes, consider this your wake-up call! Hosted by the ever-insightful Dr. Adam Friedman and sponsored by…

Trending Article Alopecia is more than just a cosmetic concern - it’s a significant quality-of-life issue for patients with autoimmune connective tissue diseases (ACTDs) such as SLE, MCTD, Sjogren syndrome, UCTD,…

Trichoscopy in Skin of Color: Uncovering Overlapping Alopecia Trichoscopy is a critical tool in diagnosing hair disorders, but findings can vary in skin of color, requiring a tailored approach to…

Berberine in Dermatology: A Natural Ally for Complex Skin Conditions? Berberine, a plant-derived alkaloid long used in traditional medicine, is gaining traction as a complementary therapy in dermatology. With its…

Post-Surgical Bleeding in Dermatology: Risk, Management, and Intervention Postoperative bleeding is one of the most common complications in dermatologic surgery, potentially leading to hematoma formation and impaired healing. While careful…

ICI Therapy and Hair Loss: A Rare but Impactful Side Effect Immune checkpoint inhibitors (ICIs) have transformed cancer treatment, empowering the immune system to target tumors more effectively. But with…

Microbiome Matters: Can Your Moisturizer Restore Balance? The skin microbiome is more than just a trendy buzzword - it is a critical player in the pathophysiology of atopic dermatitis and…

Did You Miss It? In December JDD posted a March article early online. If you have not read it yet, you do not want to miss it! Social media is…

Featured Video Abstract Check out our all new video abstract from Patricia K. Farris, MD, where she discusses acetyl dipeptide-31 amide as a novel cosmetic anti-inflammatory peptide that demonstrates anti-aging,…

Featured Podcast What a time to be a psoriasis patient, decades into the golden age of management strategies. With an embarrassment of treatment riches, all patients are clear right? Slow…

Intralesional Steroids vs. Cryotherapy: Which Wins for Alopecia Areata? Alopecia Areata (AA) remains an enigmatic condition with treatment options offering varying degrees of success. While intralesional corticosteroids are the first-line treatment,…

Hyaluronidase and HA Fillers: Does One Dose Fit All? Not all HA fillers dissolve the same way. A new study reveals that HA concentration is key in determining hyaluronidase effectiveness,…

Trending Article We know cold weather dries out skin, but did you know it can also cause full-blown medical conditions? Cold temperatures compromise the skin’s barrier, triggering inflammation, water loss,…

Access Denied: Medicaid's Barrier to Dermatologic Treatment Vitiligo and alopecia areata (AA) are not just cosmetic concerns—they profoundly affect patients' quality of life. While the FDA has approved innovative JAK…

Patchy Hair Loss: When Alopecia Areata Isn't the Answer Not all patchy hair loss is alopecia areata. Two recent cases reveal cutaneous lupus erythematosus (CLE) mimicking AA, highlighting a critical…

Sonidegib for laBCC: A Neoadjuvant Game Changer? Neoadjuvant Hedgehog Pathway Inhibitors (HPIs) are reshaping the approach to locally advanced basal cell carcinoma (laBCC), but tolerability remains a concern. A recent…

Featured Case Report Could your patient's go-to antiseptic be sabotaging sperm quality? PVP-I (povidone-iodine) is a trusted antimicrobial, but a recent case raises concerns about its impact on male fertility.…

A Spotlight on Skin Health As February unfolds, so does an important reminder—this month is National Cancer Prevention Month. For dermatologists, it's a time to reinforce awareness, education, and proactive…

JDD Spotlight: A Novel Topical Approach for Seborrheic Keratoses? Could a new topical formula change the way we manage seborrheic keratoses? In a pilot study, a unique blend of antioxidants,…

A recent Journal of Drugs in Dermatology study about a micropeptide with anti-aging and anti-inflammatory effects made news in Dermatology Times. The study, “Acetyl Dipeptide-31 Amide: A Novel Cosmetic Anti-Inflammatory…

JDD Spotlight: Guselkumab's 5-Year Promise in Psoriasis Curious about long-term breakthroughs in psoriasis care? A recent pooled analysis from the Phase 3 VOYAGE studies hints that guselkumab might be a…

Check out our all-new JDD Video Abstract from Naiem T. Issa, MD, PhD, who discusses how new formulations of acyclothymidine dinucleosides reduces the damaging effects of ultraviolet radiation in an…

Dupilumab Treatment Improves Lichenification in Atopic Dermatitis in Different Age and Racial Groups
JDD Spotlight: Dupilumab Shows Rapid, Sustained Relief for Lichenification in AD A new pooled analysis from five clinical trials has revealed that dupilumab significantly improves lichenification in moderate to severe…

JDD Spotlight The PROAK study evaluated real-world outcomes in patients with actinic keratosis reated with tirbanibulin 1% ointment over 24 weeks. Early improvements in quality of life were noted as…

From the Vault Do collagen supplements really work for skin? Collagen supplements are booming in the skincare world, but do they truly deliver on their promises? With little regulation around…

PSO Exciting: Clinical Pearls and Emerging Therapies For Psoriasis The field of dermatology continues to evolve at a rapid pace, bringing groundbreaking research from the lab to the clinic. As…

Trending Article Alert Integrated skincare—the future of aesthetic outcomes? A roundtable, featured at the Thriving in Diversity webinar series, brought together leading dermatologists and cosmetic surgeons to discuss how integrated…

Did You Miss It? How does the roflumilast cream vehicle compare? For patients with inflammatory dermatologic conditions, a hydrating vehicle is key to improving the skin barrier without irritation. But…

Listen in on a panel discussion on the use of colloidal oat in skin care. Drs Friedman, Chovatiya, and Heath will share their insights on the history and science behind…

From the Vault Isotretinoin remains the gold standard for treating severe nodulocystic acne, yet concerns about its potential psychiatric effects continue to spark debate. While high-quality studies have found no…

Featured Podcast Managing alopecia is already anxiety provoking enough, but throw some inflammatory scalp diseases into the mix...ok deep breaths...think of a happy place. So happy your brain brought you…

Featured Article Acanthosis nigricans disproportionately affects individuals with darker skin tones, yet no FDA-approved treatment currently exists. As the demand for effective therapies grows, the dermatology community faces a critical challenge:…

Check out our all-new JDD Video Abstract from Zoe Diana Draelos, MD, who assesses the vehicle for roflumilast cream compared to a ceramide-containing moisturizing cream in treating mild eczema.

Featured Article Have you missed this November 2024 article that's been making headlines? GLP-1 receptor agonists (GLP1RAs), including liraglutide and semaglutide, are proving effective beyond their established roles in weight…

Featured Article Who is at risk for hypertrophic scars and keloids? A study of 6,249 patients reveals that hypertrophic scars and keloids are significantly more common in Black/African American individuals…

Featured Article Could vitiligo lower melanoma risk—or might it mask it? The intricate relationship between these conditions takes a surprising turn in this compelling case of melanoma on a non-sun-exposed site…

Featured Podcast Cancer has met its match with the rise of new targeted therapies. However with the expanding cancer busting armament comes with the baggage of new and emerging cutaneous…

Featured Article While neuromodulators are exceptionally safe for cosmetic use, complications such as neutralizing antibody formation and eyelid ptosis can occasionally occur. Experts participating in the “Thriving in Diversity” webinar…

Glabellar Contraction Patterns in Black Patients: Implications for Botulinum Toxin Treatment Botulinum toxin is widely used for treating dynamic glabellar lines, but contraction patterns in Black patients had not been…