Found 25 articles for: "hyperpigmentation"
An Investigator-Developed Regimen for Treatment and Prevention of Post-Inflammatory Hyperpigmentation in Skin of Color
April 2026 | Volume 25 | Issue 4 | Original Article | 330 | Copyright © April 2026
Background: There is an unmet demand for a post-inflammatory hyperpigmentation (PIH) treatment and prevention that is not only effective and accessible, but also safe to use in d...
Read MoreHydroquinone and Emerging Depigmenting Agents: Clinical Guidelines, Regulatory History, and Global Safety Considerations
April 2026 | Volume 25 | Issue 4 | Original Article | 363 | Copyright © April 2026
Hydroquinone has long served as the gold standard for hyperpigmentation treatment, but safety concerns, regulatory changes, and growing interest in non-hydroquinone therapies have prompted reeval...
Read MoreRapid Clearance of Lichen Planus With Topical Tapinarof
April 2026 | Volume 25 | Issue 4 | Case Reports | 381 | Copyright © April 2026
Background: Lichen planus (LP) is an auto-inflammatory idiopathic condition affecting skin, mucous membranes, hair follicles, and nails that presents as pruritic, violaceous papu...
Read MoreEfficacy and Safety of Cysteamine-Isobionic Amide Complex in the Treatment of Periorbital Hyperpigmentation
February 2026 | Volume 25 | Issue 2 | Original Article | 140 | Copyright © February 2026
Periorbital hyperpigmentation is a common yet challenging cosmetic concern due to the thin, vascular, and pigment-prone nature of periocular skin, as well as its multifactorial etiology. Discolor...
Read MoreA Novel Topical Agent for the Management of Hyperpigmentation, Including Melasma and Age Spots
January 2026 | Volume 25 | Issue 1 | Original Article | 75 | Copyright © January 2026
Background/Objectives: Melasma and age spots are among the most persistent and difficult-to-treat forms of hyperpigmentation. While traditional therapies offer some clinical effi...
Read MoreEvaluation of an Advanced, Multimodal Skin Tone Correcting Serum in Participants With Mild-to-Severe Dyschromia and Hyperpigmentation
January 2026 | Volume 25 | Issue 1 | Original Article | 36 | Copyright © January 2026
Background: A new multimodal skin tone correcting serum formulated with b.r.y.t.e.r. (brown, red, and yellow tones with enhanced resurfacing) technology (EV-I) targets brown, red...
Read MoreClinical Evaluation of a Thiamidol-Based Regimen With SPF Compared With SPF Alone for Facial Hyperpigmentation
January 2026 | Volume 25 | Issue 1 | Original Article | 48 | Copyright © January 2026
Read MoreA Randomized, Controlled, Split-Face, Double-Blind Study Comparing Topical Malassezin to Hydroquinone 4% for Melasma
January 2026 | Volume 25 | Issue 1 | Original Article | 25 | Copyright © January 2026
Background: Previous studies have documented the capacity of malassezin to brighten the skin. It represents a novel agent for the treatment of hyperpigmentation.Photodistributed Hyperpigmentation Associated With COVID-19 Vaccination
January 2026 | Volume 25 | Issue 1 | Case Reports | 93 | Copyright © January 2026
Background: Although drugs are a common cause of hyperpigmentation, the pathogenesis is unclear and varies based on the offending agent. Classic medications associated with hyper...
Read MoreClinical Evaluation of Thiamidol-Containing Formulations for the Visual Management of Facial Hyperpigmentation
December 2025 | Volume 24 | Issue 12 | Original Article | 1195 | Copyright © December 2025
Read MoreThe Impact of Hyperpigmentation on the Lives of Patients
July 2025 | Volume 24 | Issue 7 | Original Article | 668 | Copyright © July 2025
Hyperpigmentation is a prevalent condition that disproportionately impacts individuals with skin of color, diminishing their quality of life and psychosocial well-being. There is a need to better...
Read MoreThe Impact of Increasing Skin of Color Representation in the Pre-Clerkship Dermatology Curriculum
July 2025 | Volume 24 | Issue 7 | Editorials | e50 | Copyright © July 2025
Thiamidol: A Breakthrough Innovation in the Treatment of Hyperpigmentation
June 2025 | Volume 24 | Issue 6 | Original Article | 608 | Copyright © June 2025
Cutaneous hyperpigmentation, including melasma, solar lentigines, and post-inflammatory hyperpigmentation (PIH), results in a significant impact on patients’ quality of life. Unfortunately,...
Read MoreTreatment of Acne-Induced Macular Hyperpigmentation in Fitzpatrick Skin Types V - VI: A Scoping Review
June 2025 | Volume 24 | Issue 6 | Original Article | 579 | Copyright © June 2025
Acne-induced macular hyperpigmentation (AMH) is a common issue among patients with highly melanated skin, particularly those with Fitzpatrick Skin Types (FST) V - VI, which includes nonwhite pati...
Read MoreIsobutylamido Thiazolyl Resorcinol (Thiamidol) for Combatting Hyperpigmentation: A Systematic Review of Clinical Studies
November 2024 | Volume 23 | Issue 11 | Original Article | 986 | Copyright © November 2024
Background: Tyrosinase is the rate-limiting enzyme of melanogenesis and thus an ideal inhibitory target for treating hyperpigmentation. There are many commercially available tyro...
Read MoreA Single-Center, Open-Label, Prospective Study of a 589/1319 nm Dual Wavelength Laser for the Treatment of Facial Hyperpigmentation
November 2024 | Volume 23 | Issue 11 | Original Article | 943 | Copyright © November 2024
Background: Facial hyperpigmentation, characterized by the excessive production of melanin in the skin, is a prevalent dermatological concern affecting individuals of various eth...
Read MoreExamining Racial Diversity in Hyperpigmentation and Post-Inflammatory Hyperpigmentation Clinical Trials in the United States
July 2024 | Volume 23 | Issue 7 | Editorials | e158 | Copyright © July 2024
Postinflammatory Hyperpigmentation Following Mohs Micrographic Surgery: An Observational Study
May 2024 | Volume 23 | Issue 5 | Original Article | 316 | Copyright © May 2024
Importance: Functional and cosmetic outcomes following Mohs micrographic surgery (MMS) are poorly studied in individuals with skin of color (SOC). Postinflammatory hyperpigmentat...
Read MoreComparing the Efficacy and Tolerability of Moderate to Severe Hyperpigmentation and Skin Unevenness
January 2024 | Volume 23 | Issue 1 | Original Article | 1260 | Copyright © January 2024
Dyschromia is the result of irregular facial pigmentation. These cutaneous manifestations can have a significant impact on the quality of life of those affected, especially among females and skin...
Read MoreTopical Treatments for Melasma and Post-inflammatory Hyperpigmentation
November 2023 | Volume 22 | Issue 11 | Original Article | 1118 | Copyright © November 2023
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