Tag

melasma Archives - JDDonline - Journal of Drugs in Dermatology

Dermatologist looking at skin

What’s New in Dermatology – January 2021

By Featured Articles, The Latest No Comments

Featured Article

Featured Article

Dermatologist looking at skin

In the January 2021 issue of the JDD, groups of experts reflect on lessons learned this year in several articles offering guidance and recommendations for practice management and patient care moving into the future. While in other articles, investigators share findings that aim to improve disease understanding and patient care.

In the January 2021 issue of the JDD, groups of experts reflect on lessons learned this year in several articles offering guidance and recommendations for practice management and patient care moving into the future. While in other articles, investigators share findings that aim to improve disease understanding and patient care.

 

Heather Onorati

January always represents new beginnings. It’s the time of year we tend to reflect on the past, extract insight from experience and look toward the future with new hope and understanding. It is with this in mind that our January issue couples articles based in foresight and advances.

Groups of experts reflect on lessons learned this year in several articles offering guidance and recommendations for practice management and patient care moving into the future. While in other articles, investigators share findings that aim to improve disease understanding and patient care.

In Aesthetic Office Disaster Preparedness and Response Plan, authors look to their shared experiences to provide suggestions for a proactive approach to manage possible future disaster-related events that could affect aesthetic practice operations and financial viability. Leveraging Virtual Boot Camp to Alleviate First Year Dermatology Resident Anxiety illustrates compelling levels of anxiety among incoming first-year dermatology residents and suggests that formally addressing the tenets of the specialty at the onset of PGY-2 can strengthen the foundation and boost the confidence of trainees. And, in Prescribing Isotretinoin for Transgender Patients: A Call to Action and Recommendations, authors discuss how the field of dermatology must remain on the leading edge of patient safety and advocacy issues and remain compassionate and adaptable when facing new patient care issues.

In the spirit of advancing understanding, other articles look to build the knowledge well around therapeutic techniques and disease treatment. As we continue toward a better understanding COVID-19, New York and Brazilian researchers examine the cutaneous presentations that could be clues to diagnosis in Presentation and Management of Cutaneous Manifestations of COVID-19. In the article Aesthetic ONE21 Technique for Injecting IncobotulinumtoxinA into the Forehead: Initial Experience With 86 Patients, authors report safety and efficacy from a single-center, retrospective study. Researchers present a clinical evaluation of a drug-device combination product for the topical treatment of molluscum contagiosum in A Phase 2 Open-Label Study to Evaluate VP-102 for the Treatment of Molluscum Contagiosum.

In addition, experts examine the impact of psychosocial stress on skin health, investigate efficacy of a nutraceutical supplement for promoting hair growth, discuss recommendations for absorbable suspension sutures in nonsurgical facial rejuvenation, and much more.

Heather Onorati is an experienced medical writer and editor with more than 20 years covering the dermatology industry.
January 2021 JDD 

 

Editorials

Original Articles

Case Reports

Supplements

You May Also Like

Recommendations for Preparing a Disaster Response Plan

| Aesthetics, COVID 19, Featured Articles, The Latest | No Comments
In a paper recently published by JDD, several experts developed a guide based on their own experiences navigating the challenges of this past year. In a paper recently published by…
Dermatologist looking at skin

What’s New in Dermatology – January 2021

| Featured Articles, The Latest | No Comments
In the January 2021 issue of the JDD, groups of experts reflect on lessons learned this year in several articles offering guidance and recommendations for practice management and patient care…

Top 10 Most Talked About Articles of 2020

| Featured Articles, The Latest | No Comments
As 2020 comes to a close, we are excited as we look to 2021. We are incredibly grateful to the researchers who have chosen to publish their work with JDD.…

Top 10 Most Talked About Articles of 2020

By Featured Articles, The Latest No Comments

Featured Article

Featured Article

As 2020 comes to a close, we are excited as we look to 2021. We are incredibly grateful to the researchers who have chosen to publish their work with JDD. And, we look forward to continuing to play a role in highlighting the benefits of the most promising treatments for your patients in the New Year.  

As 2020 comes to a close, we are excited as we look to 2021. We are incredibly grateful to the researchers who have chosen to publish their work with JDD. And, we look forward to continuing to play a role in highlighting the benefits of the most promising treatments for your patients in the New Year.  

 

Heather Onorati

The second half of 2020 has seen the world still trying to navigate and overcome the COVID-19 pandemic, and the practice of dermatology has been no exception. However, while still an area of focus, dermatologists have been reading, sharing and discussing studies about a variety of other conditions and treatments relevant to their patients.  

In our year-end topten list, we’re sharing the case studies, reviews and investigations published by the Journal of Drugs in Dermatology that have been downloaded and read the most in the past 12 months.  

 

As the world sought to understand the emerging Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), or coronavirus disease 2019 (COVID-19), many potential signs and symptoms were investigated in connection with the virus, leading dermatologists to also grapple with identifying potentially afflicted patients. In a case study published early in the pandemic, authors in Cairo, Egypt, looked at whether a reported case of a pityriasis rosea-like rash could be connected with COVID-19. 

While COVID-19 remains a topic of interest, other issues like the use of neutraceuticals, approaches to treating melasma and hyperpigmentation, countering hair loss, and calming dermatitis have drawn attention.   

Nutrition and supplementation are topics of interest across medicine for their potential roles in overall health and wellness, including skincare. A literature review published in early 2019 examined the benefits of collagen supplementation in skin healing and anti-aging. The authors reported on a total of 11 studies that included 805 patients being treated for a range of issues from decubitus ulcers to anti-aging. In their analysis, the authors noted that collagen supplementation appeared to be promising with potential improvements in elasticity, hydration and dermal collagen density; however not all supplements are created equal and patients should be counselled with regard to ingredients and expectations, they noted. Another study that explored the use of a neutraceutical supplement for the treatment of hair loss highlighted botanical ingredients that may mitigate triggers for hair loss and help to restore balance to the follicle.   

In line with patient interest in “natural” treatments, investigators examined the mechanism of action for observed dermatologic benefits of colloidal oatmeal and found that extracts of colloidal oatmeal decreased pro-inflammatory cytokines in vitro. 

 

“Clinical evaluations showed that the colloidal oatmeal skin protectant lotion significantly improved dryness, scaling and roughness as early as 1 day after use, and these improvements were maintained over the duration of the study with continued use of the lotion,” the authors wrote. 

Among the investigations into treatments for common but challenging conditions, authors from the University of Kansas Medical Center, Kansas City, KS, reported on a case of chronic bilateral nasolabial fold seborrheic dermatitis. They hypothesized that Crisaborole 2% ointment, a PDE4 inhibitor would reduce the inflammation. After 2 treatments per week for 4 weeks, the investigators observed a notable reduction in scaling and erythema on the treatment site.  

Another commonly seen condition, xanthelasma palpebrae, can be a significant cosmetic concern for patients. In a case study published in 2016, researchers report on a case in which they used a hyfrecator for superficial tissue destruction resulting in excellent cosmetic results, the authors showed. 

Melasma and hyperpigmentation are among the challenging conditions dermatologists see. One study still garnering attention is an investigation into the benefit of Vitamin C plus iontophoresis. Investigators observed a mean 73% improvement in abnormal pigmentation after treatment combining Vitamin C with a full-face iontophoresis mask. A mean improvement of 15.7 on the Melasma Area and Severity Index was also noted.  

A review of 10 studies examining the efficacy of retinoids and azelaic acid for the treatment of acne and subsequent post-inflammatory hyperpigmentation in skin of color reported growing evidence that retinoids are well-tolerated and could be considered as first-line therapies to treat acne people with skin of color. In addition, azelaic acid may offer improvement in both acne and hyperpigmentation, the authors noted.  

Finally, a more recent review evaluated 35 randomized controlled trials of topical agents for the treatment of melasma found strong evidence for the recommendation of cysteamine, triple combination therapy, and tranexamic acid. 

As 2020 comes to a close, we are excited as we look to 2021. We are incredibly grateful to the researchers who have chosen to publish their work with JDD. And, we look forward to continuing to play a role in highlighting the benefits of the most promising treatments for your patients in the New Year. 

Heather Onorati is an experienced medical writer and editor with more than 20 years covering the dermatology industry.
Read the top 10 most discussed articles in 2020: 

 

You May Also Like

Recommendations for Preparing a Disaster Response Plan

| Aesthetics, COVID 19, Featured Articles, The Latest | No Comments
In a paper recently published by JDD, several experts developed a guide based on their own experiences navigating the challenges of this past year. In a paper recently published by…
Dermatologist looking at skin

What’s New in Dermatology – January 2021

| Featured Articles, The Latest | No Comments
In the January 2021 issue of the JDD, groups of experts reflect on lessons learned this year in several articles offering guidance and recommendations for practice management and patient care…

Top 10 Most Talked About Articles of 2020

| Featured Articles, The Latest | No Comments
As 2020 comes to a close, we are excited as we look to 2021. We are incredibly grateful to the researchers who have chosen to publish their work with JDD.…

The Therapeutic Use of Antioxidants for Melasma

By Aesthetics No Comments

Featured Article

Featured Article

With a well demonstrated impact on quality of life, melasma is a common cause for seeking dermatologic care. There is no universally efficacious therapy, so combination treatment is preferred. Therapies include topical hypopigmenting agents, laser treatment, microneedling, chemical peels, radiofrequency, and oral medications.1 Furthermore, it is critical for patients to avoid exacerbating factors.

Read more

In this review, authors discuss the well-defined role of oxidative stress in melasma and the therapeutic efficacy of various antioxidants for patients suffering from melasma, focusing on studies investigating the role of vitamin C, azelaic acid, cysteamine, glutathione, carotenoids, and numerous other antioxidants in disorders of hyperpigmentation.

Kayla M. Babbush BS, Remy A. Babbush BS, Amor Khachemoune MD FAAD FACMS

 

Melasma is a chronic and acquired skin disorder of hyperpigmentation that presents with symmetric hypermelanosis of sun exposed areas, especially the face. Disease prevalence, ranging from 1 to 50%, varies with gender, ethnicity, skin phenotype, and sun exposure.

The pathogenesis of melasma is incompletely understood, which poses a challenge for disease management. Causative factors include genetics, ultraviolet (UV) radiation, cosmetics, pregnancy, hormonal therapy, phototoxic drugs, and various medications.

Melasma is evaluated by Melasma Area and Severity Index (MASI) score, modified MASI (mMASI) score, Melasma Quality of Life Scale (MelasQoL), colorimetry, and mexametry.

With a well demonstrated impact on quality of life, melasma is a common cause for seeking dermatologic care. There is no universally efficacious therapy, so combination treatment is preferred. Therapies include topical hypopigmenting agents, laser treatment, microneedling, chemical peels, radiofrequency, and oral medications.1 Furthermore, it is critical for patients to avoid exacerbating factors.

The skin, a protective organ critical in homeostasis, is the site of numerous biochemical processes, including the generation of free radicals, namely reactive oxygen and nitrogen species. Reactive oxygen species (ROS) are necessary for biological signaling processes, but, in excess, ROS can damage biomolecules.3 There is clear evidence of oxidative stress in melasma.

Read Full Article Now
Article Cited in this Post

You May Also Like

Recommendations for Preparing a Disaster Response Plan

| Aesthetics, COVID 19, Featured Articles, The Latest | No Comments
In a paper recently published by JDD, several experts developed a guide based on their own experiences navigating the challenges of this past year. In a paper recently published by…
Dermatologist looking at skin

What’s New in Dermatology – January 2021

| Featured Articles, The Latest | No Comments
In the January 2021 issue of the JDD, groups of experts reflect on lessons learned this year in several articles offering guidance and recommendations for practice management and patient care…

Top 10 Most Talked About Articles of 2020

| Featured Articles, The Latest | No Comments
As 2020 comes to a close, we are excited as we look to 2021. We are incredibly grateful to the researchers who have chosen to publish their work with JDD.…

Melasma: Treatment Pearls from the Expert

By Derm Community, ODAC No Comments

Dermatology News

Video Pearls

E. Victor Ross, MD, is a dermatologist specializing in laser surgery of the skin. He uses a broad array of technologies to reduce red and brown skin lesions, wrinkles and unwanted hair, improve spider veins of the legs and improve the appearance of scars, including acne scars.

Learn More

Melasma: Treatment Pearls from the Expert

featuring Dr. Vic Ross

Journal of Drugs in Dermatology partners Next Steps in Derm and ODAC Dermatology Aesthetic and Surgical Conference interviewed Dr. Vic Ross, Director of the Scripps Clinic Laser and Cosmetic Dermatology Center in San Diego on his approach and the various interventions he uses for the treatment of Melasma.

More On Melasma

Melasma is a commonly condition that mostly affects women with Fitzpatrick skin types III-VI with prominent brown pigmentation with or without an underlying erythema. Treating Melasma is challenging, due to its chronic nature.

Explore Melasma Articles

ODAC Orlando Dermatology, Aesthetic & Surgical Conference

ODAC Dermatology, Aesthetic and Surgical Conference (ODAC) is a distinguished ACCME accredited dermatology conference designed to meet the needs of medical and aesthetic dermatology providers in the 21st century. Founded in 2003 by dermatology pioneer, Dr. Perry Robins, the ODAC Dermatology Conference provides nearly 700 dermatologists, residents, nurse practitioners and physician assistants with important annual updates and fresh practical pearls in the field of medical, cosmetic and surgical dermatology in a highly interactive format.

Reasons to Attend ODAC 2021

  • Discuss the next generation of diagnostic approaches and evidence-based dermatology treatments
  • Observe cutting-edge procedures and techniques with live demonstrations of novel products and emerging technologies
  • Review clinical trial results and discuss case-studies in both large and small group settings
  • Cultivate relationships with colleagues and leaders actively shaping the future of dermatology
  • Earn CME –  up to 31 AMA PRA Category 1 Credits™
Register for ODAC 2021 Now

You May Also Like

Sign Up To Attend Free ODAC Virtual Workshops

| Events | No Comments
Sign up now to attend Free ODAC Virtual 2021 Workshops Sign up now to attend Free ODAC Virtual 2021 Workshops The virtual ODAC conference, taking place January 14 – 17,…

Insights On the Pediatric, Adolescent & Adult AD Patient

| Atopic Dermatitis, Podcast Highlights | No Comments
iTunes Google Play Stitcher TuneIn Dr. Peter Lio, Dr. Lindsay Finklea & Dr. Adam Friedman   You can't truly understand someone until you walk a mile in their shoes. This…

Insights On the Pediatric, Adolescent & Adult AD Patient

| Podcast | No Comments
You can't truly understand someone until you walk a mile in their shoes. This is true to so many aspects of daily life, especially when it comes to chronic, relapsing,…

November JDD Highlights

By JDD Highlights
The November 2019 JDD is here!
This month, we focus on lasers, light sources, and devices! Take a look at our editorial highlights, editor’s picks, and more below:
Get More from the JDD - Subscribe Today!

You May Also Like

Derm Community
June 16, 2020

A Must-Read: The Business of Dermatology

Edited by Drs. Jeffrey S. Dover and Kavita Mariwalla, and authored by impressive experts in the field, The Business of Dermatology offers a comprehensive guide to opening, maintaining, and sustaining…
Derm CommunityODACPhotoprotectionSkin Cancer
June 1, 2020

Controversies in Photoprotection

Adam Friedman, MD, FAAD is Professor and Interim Chair of Dermatology and serves as Residency Program Director, Director of Translational Research, and Director of the Supportive OncodermatologyProgram in the Department…
Derm CommunityODACSkin Cancer
May 18, 2020

Does This Skin Cancer Really Need Mohs?

The discussion was led by Dr. Vishal Patel and Dr. Sailesh Konda, and was moderated by Dr. William Hanke. In recognition of National Skin Cancer Month, the Journal of Drugs…