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New Treatment for Dyshidrotic Eczema

By April 26, 2021May 10th, 2021No Comments

Struggling with how to treat dyshidrotic eczema of the hands, palms, fingers or feet? We explore the use of a new medication in the treatment of dyshidrotic eczema and common patient questions.

What is dyshidrotic eczema?

Dyshidrotic eczema is a skin condition similar to atopic dermatitis or contact dermatitis that mainly effects the hands, fingers, palms and feet.  It is sometimes referred to as hand eczema, dyshidrosis or pompholyx and it’s location makes it difficult to treat. Symptoms include intensely itchy, painful blisters that can peel, scale and split the skin.  Some have likened dyshidrotic eczema to tapioca pudding.

What causes dyshidrotic eczema?

Dyshidrotic eczema is often thought to be a manifestation of eczema-like conditions.  A history of atopic dermatitis, allergic contact dermatitis, exposure to irritants, smoking, sunlight and hyperhidrosis (excessive sweating) have been associated.

Is it contagious?

Dyshidrotic eczema is not contagious. You cannot catch it from someone who has it or give it to someone else.

New, potential treatment for dyshidrotic eczema.

The Journal of Drugs in Dermatology (JDD) has published case reports results including the successful treatment of dyshidrotic eczema with dupliumab.  Although additional controlled clinical studies are warranted, dupliumab has proven useful in the management of multiple patients with dyshidrotic eczema.  Dupilumab is an interleukin 4 receptor-α antagonist that inhibits the action of both IL-4 and IL-13, thus blocking two important cytokines responsible for Th2-mediated inflammation.

The JDD case studies are available to learn more.

Two Cases of Recalcitrant Dyshidrotic Eczema Treated With Dupilumab

May 2021 | Volume 20 | Issue 5 | Features | 5273 | Copyright © May 2021

Authors: Ryan A. Gall, MD, John D. Peters, MD and Alyson J. Brinker, MD

Dupilumab in the Treatment of Dyshidrosis: A Report of Two Cases of Dyshidrotic Eczema

March 2018 | Volume 17 | Issue 3 | Case Reports | 355 | Copyright © March 2018

Authors: Gillian K. Weston, MD, Jette Hooper, Bruce E. Strober, MD, PhD

A Case of Complete Resolution of Severe Plantar Dyshidrotic Eczema With Dupilumab

February 2019 | Volume 18 | Issue 2 | Editorials | 211 | Copyright © February 2019

Authors: Sonali Nanda MS, Nicole Nagrani BS, Flor MacQuhae MD, Anna Nichols MD, PhD

Dyshidrotic Eczema Images (click to enlarge):

Dyshidrotic eczema picture on the soles of feet


Dyshidrotic eczema picture of the hands