FULL SUPPLEMENT: Prebiotic Skincare Management of Atopic Dermatitis & Xerosis in Diverse Ethnically Patients

March 2024 | Volume 23 | Issue 3 | SF395747s1 | Copyright © March 2024


Published online March 1, 2024

Hawasatu Dumbuya PhD

La Roche-Posay Laboratoire Dermatologique, L'Oréal USA, New York, NY

Abstract
Atopic Dermatitis (AD) is a chronic relapsing inflammatory skin disease associated with a significant patient burden on quality-of-life. Rising evidence demonstrate skin microbiome playing an essential role in AD pathogenesis. A decrease in skin microbial diversity, particularly an overabundance of Staphylococcus aureus colonization, is observed on AD lesional skin, plus is associated with disease severity.



In this supplement:

Recent Advances in Skincare Management of Atopic Dermatitis in Diverse Racial and Ethnic Groups

Atopic Dermatitis (AD) is a chronic relapsing inflammatory skin disease associated with a significant patient burden on quality-of-life. Rising evidence demonstrate skin microbiome playing an essential role in AD pathogenesis. A decrease in skin microbial diversity, particularly an overabundance of Staphylococcus aureus colonization, is observed on AD lesional skin, plus is associated with disease severity.

Read the article here.

Atopic Dermatitis Skincare and Impact on Quality of Life for Patients with Skin of Color

Atopic Dermatitis (AD) epidemiologic studies report a higher incidence and prevalence among populations with skin of color (SOC). Additionally, differences in AD underlying gene mutations and skin morphology are observed to lead to frequent and prominent xerosis, pruritus, and pigmentary sequelae in patients of color. However, populations with SOC are underrepresented in dermatology clinical trials, including AD. This article reviews the nuances in AD epidemiology, clinical presentation, and impact on quality-of-life among populations with SOC, plus highlight the role of skincare in AD management.

Read the article here.

Efficacy of a Prebiotic Skincare Regimen on Improving Mild Atopic Dermatitis and Severe Xerosis in Diverse Ethnically Patients

Atopic Dermatitis (AD) is a chronic relapsing inflammatory skin disease associated with a significant patient burden on quality-of-life. Given skin barrier including skin microbiome changes are linked to AD pathogenesis, prebiotic emollients are shown to improve disease symptoms and maintain skin barrier integrity, normalizing skin microbiota. In this study, we evaluated the efficacy and safety of a prebiotic skincare routine in improving AD and xerosis, and ultimately quality-of-life in ethnically diverse patients. A total of 140 subjects from different racial/ethnic backgrounds, aged 3-80 years old with skin phototypes I-VI, and presenting with mild-AD or severe xerosis completed study.

Read the article here.