Issue Archive
May 2025 | Volume 24 | Issue 5
Editorials
Exploring the Scope of Melanoma Educational Content on Instagram
Citation: Swearingen A, Olagun-Samuel C, Sikora M, et al. Exploring the scope of melanoma educational content on Instagram. J Drugs Dermatol. 2025;24(5):e34. doi:10.36849/JDD.8751...
Read MoreThe Impact of Geographic Dermatologist Density on Melanoma Mortality
Synergistic Mechanisms of 5-Fluorouracil and Imiquimod in the Treatment of Actinic Keratoses
Citation: Regester RM, Cannella AC, Thiele GM, et al. Synergistic mechanisms of 5-fluorouracil and imiquimod in the treatment of actinic keratoses. J Drugs Dermatol. 2025;24(5):e35....
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Original Articles
Clindamycin Phosphate 1.2%/Adapalene 0.15%/ Benzoyl Peroxide 3.1% for Acne: Results From A 6-Month Open-Label Study
Background: Treatment of acne may require many months of treatment before maximal benefits are observed, and acne sequelae (eg, scarring, dyspigmentation) can persist long after lesion resolution. In ...
Read MoreRandomized-Controlled Trial Comparing Safety and Efficacy of Repairing Balm vs Topical Antimicrobial for Post-Procedural Wounds
Background: Actinic keratoses (AK) are pre-cancerous, intraepidermal lesions that exist on a continuum with squamous cell carcinoma. Cryotherapy using liquid nitrogen freezing is the most common metho...
Read MorePlacental Allograft Reconstruction of Cutaneous Wounds Following Mohs Surgery: A Propensity Score-Matched Comparative Cost-Effectiveness Analysis
Background: The purpose of this study was to examine the cost-effectiveness of placental allograft as a nonoperative surrogate to autologous tissue-based methods of defect reconstruction on the face, ...
Read MoreEfficacy and Tolerability of a Cream in Aging Skin
Background: The clinical presentation of photodamaged and aged skin includes fine lines, wrinkles, and pigmentation changes, which are related to the amount of water in the epidermis. Use of moisturiz...
Read MoreEfficacy and Safety of Hedgehog Inhibitors for Advanced Basal Cell Carcinoma: An Expert Consensus Panel
Background: Hedgehog inhibitors (HHIs) can be used to treat patients with locally advanced basal cell carcinoma (laBCC) who are not candidates for surgery or radiation or whose tumors have recurred fo...
Read MoreIs Upadacitinib Cardioprotective in Chronic Inflammatory Diseases? A Review of Major Adverse Cardiovascular Events and Venous Thromboembolism in Atopic Dermatitis
Background: Atopic dermatitis (AD) is a chronic inflammatory skin condition associated with risk of cardiovascular disease (CVD), potentially mediated by persistent systemic inflammation. Upadacitinib...
Read MoreMedical and Surgical Management of Multifocal Superficial Basal Cell Carcinoma
Background: Multifocal superficial basal cell carcinoma (sBCC) is a subtype of BCC characterized by subclinical extension of noncontiguous tumor islands and high recurrence rates. Mohs micrographic su...
Read MoreTopical Corticosteroid Potencies: Reimagining A New Universal Classification System
Topical corticosteroids (TCS) are an effective and generally tolerable class of medications frequently used for a wide variety of dermatologic conditions. There are many currently available TCS, which...
Read MoreClinical Features and the Management of Drug-Induced Eruptive Keratoacanthoma and Squamous Cell Carcinoma: A Review of 172 Cases
Background: The sudden appearance of keratoacanthomas (KA) and squamous cell carcinomas (SCC) is a serious complication of several oncologic and immunomodulatory medications. The development of numero...
Read MoreThe Comparison Between Conventional Photodynamic Therapy and "Painless"TM Photodynamic Therapy in the Treatment of Actinic Keratosis: A Mini Review
Actinic keratosis is a prevalent skin condition associated with prolonged exposure to ultraviolet radiation and serves as a precursor to squamous cell carcinoma. This condition arises from DNA mutatio...
Read MoreCutaneous Immune-Related Adverse Events Associated With Immunotherapy in Patients With Melanoma
Background: Cutaneous immune-related adverse events (irCAEs) have been commonly reported as a consequence of immune checkpoint inhibitors (ICIs) for the treatment of advanced stage III and stage IV me...
Read MoreEndocrine Mucin Producing Sweat Gland Carcinoma Treated With Mohs Micrographic Surgery: A Systematic Review
Background: Endocrine Mucin Producing Sweat Gland Carcinoma (EMPSGC) is a low-grade, cutaneous adnexal neoplasm. It is believed to have a potential for local recurrence as well as distant metastases i...
Read MoreSquamous Cell Carcinoma In Situ on High-Risk Sites and With Larger Sizes Require More Stages for Clearance With Mohs Surgery
Background: Few studies have evaluated Mohs micrographic surgery (MMS) for the treatment of squamous cell carcinoma in situ or evaluated the results by Mohs Appropriate Use Criteria. Objective: Evalu...
Read MoreSurgical Outcomes of Cylindrocarcinoma Treated With Mohs Micrographic Surgery and Excision: A Systematic Review
Background: Cylindromas are benign adnexal tumors often associated with conditions such as Brooke-Spiegler Syndrome and familial cylindromatosis. Cylindromas can undergo malignant transformation into ...
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Features
The Practical Side Effects Experienced in Patients Treated With Medications Approved for Melanoma
Background: Melanoma continues to remain one of the most feared malignancies among patients and dermatologists. Significant strides have been made in expanding the treatment arsenal with systemic medi...
Read MoreRising Influence of Artificial Intelligence: Trends in Large Language Model Usage in Dermatology Residency Personal Statements
With the public release of ChatGPT before the 2024 dermatology residency application cycle, applicants gained access to an advanced language model capable of generating or enhancing personal statement...
Read MoreAll Things Acids: A Primer on Alpha Hydroxy, Beta Hydroxy, and Polyhydroxy Acids
Citation: Vidal SI, Menta N, Friedman A. All things acid: a primer on alpha hydroxy, beta hydroxy, and polyhydroxy acids. J Drugs Dermatol. 2025;24(5):549-548. ...
Read MoreEvaluating Postoperative Outcomes of Mohs Surgery in the Elderly: A Retrospective Review of Large Repairs
Background: As the geriatric population, defined by the National Institute on Aging as 65 years and older, continues to grow exponentially, understanding how age impacts the treatment of cutaneous mal...
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Case Reports
Successful Treatment of Sacral Pressure Injury With ACU-D1
Pressure injuries, previously known as pressure ulcers, commonly affect elderly patients in the sacral area, resulting in a sacral pressure injury. The mainstay of treatment is supportive care, includ...
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Departments
FULL SUPPLEMENT: Nordic European Cutaneous Oncodermatology Management (Necom 6): A Practical Algorithm Integrating Skincare for the Prevention and Treatment of Cutaneous Side Effects of Hormonal Cancer Therapy
FULL SUPPLEMENT: Defining and Treating Pre-Aging With a Novel Multi-Functional Cosmetic Peptide, Acetyl Dipeptide-31 Amide
Supplements
INDIVIDUAL ARTICLE: A Practical Algorithm for the Prevention and Treatment of Cutaneous Side Effects of Hormonal Cancer Therapy
Introduction: Hormonal therapies, typically used in the treatment of breast and prostate cancer patients, have been associated with numerous skin toxicities that can impact quality of life and interfe...
Read MoreINDIVIDUAL ARTICLE: A Scientific Approach to Defining, Evaluating, and Treating Pre-Aging With a Cosmetic Regimen Containing a Novel Cosmetic Peptide, Acetyl Dipeptide-31 Amide (AP31)
Background: Patients experiencing signs of pre-aging in their 20s and early 30s desire solutions including topical skincare and cosmetic procedures to help preserve skin quality and function.
