Issue Archive
October 2022 | Volume 21 | Issue 10
Editorials
Annual Trends in Medicare Part D Prescription Claims for Dupilumab 2017 to 2019
Disease control for moderate to severe atopic dermatitis (AD) has been primarily achieved with phototherapy and non-specific immunomodulators, cyclosporine, and methotrexate. These treatments have, ho...
Read MoreSocial Media Platforms as a Resource for Vitiligo Support
Social media use among dermatology patients is ubiquitous, with estimates of over 80% of patients using social media to learn about their dermatologic conditions. Vitiligo is an autoimmune disease lea...
Read MoreA Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss
Hair loss, specifically androgenetic alopecia (AGA), is a common outpatient dermatology complaint. AGA occurs in men and women, results from the effect of dihydrotestosterone miniaturizing scalp folli...
Read MoreA Retrospective Study of Calcinosis Cutis in Patients With Systemic Lupus Erythematosus
Calcinosis cutis (CC) is a very rare and poorly characterized finding in systemic lupus erythematosus (SLE).1 In this retrospective study, we present our experience of 10 individuals with SLE who deve...
Read MoreA Retrospective Review of Tofacitinib in the Treatment of Refractory Dermatomyositis
Dermatomyositis (DM) is an autoimmune myopathy with characteristic dermatologic features.1 Tofacitinib is an immunomodulator with proven efficacy against numerous immune-mediated disorders, including ...
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Original Articles
The Role of Antihistamines and Dupilumab in the Management of Alopecia Areata: A Systematic Review
Background: Approximately 30% to 40% of alopecia areata (AA) patients have atopic dermatitis. Studies suggest that antihistamines and dupilumab may be effective treatments; however, the potential bene...
Read MoreEvolving Concepts in Psoriasis: Special Considerations for Patients With Skin of Color, Skin Barrier Dysfunction, and the Role of Adjunctive Skin Care
Background: Despite considerable advances in our understanding of the pathogenesis and treatment of psoriasis, data pertaining to racial/ethnic variations, effects on barrier function, and the potenti...
Read MoreTreatment and Maintenance of Cutaneous Rosacea in Latino Skin Types With Prescription Medications and Non-Prescription Cleansers and Moisturizers as Adjuncts: A Review
Background: Rosacea is an inflammatory dermatosis with at least a ten percent prevalence reported among white adults. Rosacea occurs in nonwhite populations, but prevalence data is limited.
Meth...
Read MoreMeasuring and Improving Adherence to Crisaborole 2% Ointment in Patients With Atopic Dermatitis
Background: Atopic dermatitis (AD) is an inflammatory skin condition with dry, scaly, and intensely itchy skin. Treatment failure is the result of poor adherence.
Objective: In this study, we as...
Read MorePhase 2 Trial of Topical Thykamine in Adults With Mild to Moderate Atopic Dermatitis
Background: Atopic dermatitis is a common skin disorder for which there remains an unmet need for topical pharmacotherapies that are safe and effective. This phase 2 study assessed the efficacy and sa...
Read MoreEfficacy and Safety of Tazarotene 0.045% Lotion in Caucasian Adults With Moderate-to-Severe Acne
Background: While topical retinoids are a mainstay of acne treatment, acne can manifest differently in various skin types. The objective of these post hoc analyses from two pooled phase 3 studies was ...
Read MoreArtificial Intelligence in Hair and Nail Disorders
Artificial intelligence (AI), a field of computer science, aims at simulating human intelligence with computers. Though AI has surpassed dermatologists in skin cancer detection, it still lags behind v...
Read MoreReview of Tretinoin-Benzoyl Peroxide in The Treatment of Acne Vulgaris
Background: Acne vulgaris has a multifactorial pathogenesis, and combination therapy is recommended in most patients. A tretinoin 0.1%/benzoyl peroxide 3% (Tret-BPO) cream which uses a core-shell enca...
Read MorePharmacokinetic Profile, Safety, and Tolerability of Topical Berdazimer Gel, 10.3% in Patients With Molluscum Contagiosum
Background: Berdazimer (SB206), gel 10.3% is a novel, topical, nitric oxide–releasing agent intended for molluscum contagiosum (MC) treatment.
Methods: A 12-week, open-label, multicenter t...
Read MoreDermal Safety of Tapinarof Cream 1%: Results From 4 Phase 1 Trials
Background: Tapinarof (VTAMA®; Dermavant Sciences, Inc.) is a novel, non-steroidal, topical, aryl hydrocarbon receptor agonist, FDA approved for psoriasis treatment and under investigation for ato...
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Features
Off-Label Uses of JAK Inhibitors in Dermatology
The Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway is a crucial component of immune function, and JAK inhibitors allow dermatologists to regulate this pathway in ce...
Read MoreA Narrative Review of Nicotinamide Adenine Dinucleotide (NAD)+ Intermediates Nicotinamide Riboside and Nicotinamide Mononucleotide for Keratinocyte Carcinoma Risk Reduction
Oral nicotinamide (NAM) supplementation has been shown to decrease the incidence of keratinocyte carcinoma (KC) in high-risk skin cancer patients. NAM is a nicotinamide adenine dinucleotide (NAD+) int...
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Case Reports
Why Does Facial Eczema Differ From Body Eczema?
Background: The pathophysiology of atopic dermatitis (AD) is multifactorial, influenced by genetics, skin barrier dysfunction, and environmental stressors. There is a lack of research comparing the et...
Read MoreDermatomal Granulomatous Dermatitis and Vasculitis Following Herpes Zoster Ophthalmicus
Cutaneous granulomatous dermatoses are uncommon sequelae of herpes zoster (HZ) infection that have been documented in the literature, with granulomatous vasculitis described in rare cases. Here, we re...
Read MoreLong-Term Efficacy and Safety of Omalizumab Monotherapy in a Patient With Normocomplementemic Urticarial Vasculitis
Normocomplementemic urticarial vasculitis is a rare autoimmune disorder characterized by leukocytoclasia, fibrin deposits, and extravasated erythrocytes affecting multiple organ systems. Current treat...
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Departments
Full Supplement: ALGORITHM FOR PRE-/POST- MEDICAL-ESTHETIC PROCEDURE MEASURES IN SKIN OF COLOR POPULATIONS
The aim of the new algorithm presented is to develop a clinical pathway that establishes an informed decision-making, stepwise process for optimal periprocedural care in patients with SOC who undergo ...
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Supplements
Supplement Individual Article: Algorithm for Pre-/Post-Procedure Measures in Racial/Ethnic Populations Treated With Facial Lasers, Nonenergy Devices, or Injectables
Background: Cosmetic procedures with lasers, nonenergy devices, and injectables are increasing in popularity among patients with skin of color. Published algorithms address measures to reduce side eff...
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