INTRODUCTION
Atopic dermatitis (AD) is described as an inflammatory skin condition in which patients present with dry, scaly, and intensely itchy skin.1 A number of treatment methods are available to these patients, including corticosteroids, topical calcineurin inhibitors, and antimicrobial therapies.2 In December 2016, a non-steroidal topical, crisaborole 2% ointment was approved by the Food and Drug Administration (FDA) for mild to moderate atopic dermatitis in patients ages 2 years and older, with more recent approval extended to patients aged 3 months and older.3 Despite the use of topical agents as the primary treatment method, most patients with AD do not adequately respond to topical treatment.4 Topical treatment failure may be the result of poor adherence.5-7
In this study, we hypothesized that an internet-based survey intervention would improve adherence to crisaborole in children and adults with AD. This study yielded important information including the first detailed characterization of atopic dermatitis patients’ long-term adherence to topical treatment.
In this study, we hypothesized that an internet-based survey intervention would improve adherence to crisaborole in children and adults with AD. This study yielded important information including the first detailed characterization of atopic dermatitis patients’ long-term adherence to topical treatment.
MATERIALS AND METHODS
Study Design
The purpose of this study was to evaluate the impact of an internet-based survey on adherence to topical therapy using data collected by using the Medication Electronic Monitoring System (MEMS) cap fitted to a 60-gram tube of crisaborole ointment. This was a double blinded open label study of the FDA-approved medication crisaborole 2% ointment (Eucrisa) used on-label for AD.
Subjects were randomized to 1 of 2 groups; a control group and an intervention group. All patients included in the study were provided crisaborole to use. The intervention group received weekly email surveys regarding adherence for 6 weeks, then monthly thereafter for 12 months (Figure 6). Participants in both
The purpose of this study was to evaluate the impact of an internet-based survey on adherence to topical therapy using data collected by using the Medication Electronic Monitoring System (MEMS) cap fitted to a 60-gram tube of crisaborole ointment. This was a double blinded open label study of the FDA-approved medication crisaborole 2% ointment (Eucrisa) used on-label for AD.
Subjects were randomized to 1 of 2 groups; a control group and an intervention group. All patients included in the study were provided crisaborole to use. The intervention group received weekly email surveys regarding adherence for 6 weeks, then monthly thereafter for 12 months (Figure 6). Participants in both