Using 31-Gene Expression Profile in Melanoma Risk Prognosis

May 2021 | Volume 20 | Issue 5 | Editorials | 585 | Copyright © May 2021


Published online April 26, 2021

Gabriella Vasile DO,a Muneeb Ilyas DO,a Danielle Lazzara DO,b Dominique Jacobs PCOM,c Taraneh Matin DO,a Eli Saleeby MD,a Eduardo Weiss MDb

aLarkin Community Hospital Palm Springs, Hialeah, FL
bHollywood Dermatology, Hollywood, FL
cPhiladelphia College of Osteopathic Medicine, Philadelphia, PA

DISCLOSURES

Authors Vasile G, Ilyas M, Lazzara D, Jacobs D, and Matin T have no relevant conflicts of interest to disclose.
Eduardo Weiss MD is a speaker for Castle Biosciences, Inc.

REFERENCES

1. Centers for Disease Control and Prevention. Melanoma Incidence and Mortality, United States–2012–2016. USCS Data Brief, no. 9. Atlanta, GA: Centers for Disease Control and Prevention, US Department of Health and Human Services; 2019.
2. SEER Data 2017.
3. Hsueh E et al. Interim analysis of survival in a prospective, multi-center registry cohort of cutaneous melanoma tested with a prognostic 31-gene expression profile test. J Hematol Oncol. 2017; 10:152. Doi 10.1186/s13045- 017-0520-1.
4. Greenhaw BN, Zitelli JA, Broadland DG. Estimation of prognosis in invasive cutaneous melanoma: an independent study of accuracy of gene expression profile test. Dermatol Surg. 2018; 44:1494-1500. Doi: 10.1097/ DSS. 0000000000001588.
5. Gastman BR et al. Performance of a 31-gene expression profile test in cutaneous melanomas of the head and neck. Head Neck. 2019; 41: 871-879. Doi: 10.1002/hed.25473.
6. Keller J et al. Prospective validation of the prognostic 41-gene expression profiling test in primary cutaneous melanoma. Cancer Med. 2019; 8: 2205- 2212. Doi: 10.1002/cam4.2128.
7. Podlipnik S et al. Early outcome of a 31-gene expression profile test in 86 AJCC stage IB-II melanoma patients. A prospective multicentre cohort study. JEADV. 2019; 33: 857-862. Doi: 10.1111/jdv.15454

AUTHOR CORRESPONDENCE

Gabriella Vasile DO gabriellava@pcom.edu