(55.7%) experienced moderate improvement, 7 (21.8%) experienced good improvement, and 2 (6.2%) experienced mild improvement.4
The 1064 nm Q-switched Nd-YAG (QSNYL) laser has also demonstrated efficacy regarding LPP improvement. In a nonrandomized prospective pilot study, thirteen patients were treated with a 5 mm spot size, fluence of 3-4.6 J/cm2, and 5-Hz frequency. Patients underwent treatment every 4-8 weeks for an average of 5-6 total sessions. Roughly 38.4% demonstrated significant improvement (>90% clearance), 38.4% demonstrated good improvement (>75%), and 23% demonstrated marked improvement (51-75%). No patients experienced worsening of disease within 6 months post-treatment.5
Of note, many of the studies included in this analysis had small sample sizes and exhibited relatively low levels of evidence. There is very limited data regarding efficacious treatments for LPP, and the majority of available data is derived from case reports and series. This is likely a reflection of the rarity
