Treatment of Recalcitrant Generalized Granuloma Annulare With Adalimumab

December 2011 | Volume 10 | Issue 12 | Case Reports | 1466 | Copyright © December 2011


Tiago Torres MD, Teresa Pinto Almeida MD, Rosario Alves MD, Madalena Sanches MD, Manuela Selores MD

Department of Dermatology, Hospital de Santo AntÓnio, Porto, Portugal

  1. Fayyazi A, Schweyer S, Eichmeyer B, et al. Expression of IF- Ngamma, coexpression of TNFalpha and matrix metallopro- teinases and apoptosis of T lymphocytes and macrophages in granuloma annulare. Arch Dermatol Res. 2000;292:384-390.
  2. Moreland LW, Baumgartner SW, Schiff MH, et al. Treatment of rheumatoid arthritis with a recombinant human tumor ne- crosis factor receptor (p75)-Fc fusion protein. N Engl J Med. 1997;337:141-147.
  3. Van den Brande JM, Braat H, van den Brink GR, et al. Inflix- imab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease. Gastroenterology. 2003;124:1774-1785.
  4. Kreuter A, Altmeyer P, Gambichler T. Failure of etanercept therapy in disseminated granuloma annulare. Arch Dermatol. 2006;142:1236-1237.

ADDRESS FOR CORRESPONDENCE

Tiago Torres MDRua D. Manuel II s/n Edificio Consultas Externasex-CICAPPorto, Portugal 4099-001Phone:    +35191226097429    tiagotorres2002@hotmail.com