The Role of Naftifine HCl 2% Gel and Cream in Treating Moccasin Tinea Pedis

February 2016 | Volume 15 | Issue 2 | Supplement Individual Articles | 56 | Copyright © February 2016


Tracey C. Vlahovic DPM

Associate Professor and J. Stanley and Pearl Landau Faculty Fellow, Temple University School of Podiatric Medicine, Philadelphia, PA

data and cream 2% data show the possibility of managing moccasin tinea pedis in an efficacious, safe, and tolerable manner.

DISCLOSURES

The author has been a principal investigator and has served as an advisory board member for Merz, Valeant, and Pharmaderm.

REFERENCES

  1. Habif TP. Superficial Fungal Infections. In: Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 4th ed. Philadelphia (PA): Mosby (An affiliate of Elsevier); 2004: 409-56.
  2. Canavan T and Elewski B. Identifying the Signs of Tinea Pedis: A Key to Understanding the Clinical Variables. J Drugs Dermatol. 2015; 14(suppl 10): s42-s47.
  3. Evans EG, James IG, Seaman RA, Richardson MD. Does naftifine have anti-inflammatory properties? A double-blind comparative study with 1% clotrimazole/ 1% hydrocortisone in clinically diagnosed fungal infection of the skin. Br J Dermatol. 1993; 129(4):437-42.
  4. Merz Pharmaceuticals, LLC. Naftifine product monograph. 2010.
  5. Monk JP, Brogden RN. Naftifine: a review of its antimicrobial activity and therapeutic use as in superficial dermatomycoses. Drugs. 1991; 42(4):659-72.
  6. Vago T, Baldi G, Columbo D, Barbareschi M, Norbiato G, Dallegri F, et al. Effects of naftifine, terbinafine, two allylamine antifungal drugs, on selected functions of polymorphonuclear leukocytes. Antimicrob Agents Chemother. 1994; 38(11):2605-11.
  7. Ablon G, Rosen T, Spedale J. Comparative efficacy of naftifine, oxiconazole, and terbinafine in short-term treatment of tinea pedis. Int J Dermatol. 1996; 35(8):591-93.
  8. Parish LC, Parish JL, Routh HB, Avakian EV, Olayinka B, Pappert EJ, et al. A double-blind, randomized, vehicle-controlled study evaluating the efficacy and safety of naftifine cream, 2% in tinea cruris. J Drugs Dermatol. 2011; 10(10):1142-48.
  9. Stein Gold L, Parish LC, Vlahovic T, et al “efficacy and safety of naftifine hcl gel 2% in the treatment of interdigital and moccasin type tinea pedis: Pooled results from two multicenter, randomized, double-blind, vehicle-controlled trials.” J Drugs Dermatol. 2013; 12(8):911-18.
  10. Stein Gold L, Vlahovic T, Verma A, et al. Naftifine Hydrochloride Gel 2%: An Effective Topical Treatment for Moccasin-Type Tinea Pedis. J Drugs Dermatol. 2015; 14(10):1138-44.
  11. Tanuma H. Pathogenesis and treatment of hyperkeratotic tinea pedis in Japan. Mycoses. 1999; 42(1-2):21-28.
  12. Kircik L and Onumah N. Use of naftifine hydrochloride 2% cream and 39% urea cream in the treatment of tinea pedis complicated by hyperkeratosis. J Drugs Dermatol. 2014; 13(2):162.

AUTHOR CORRESPONDENCE

Tracey C. Vlahovic DPM……....................................... traceyv@temple.edu
Close Menu