Should Hyaluronic Acid Fillers Be Diluted?

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REFERENCES

1. Borrell M, Leslie DB, Tezel A. Lift capabilities of hyaluronic acid fillers. J Cos & Laser Ther 2011;13:21-7
2. Prestwich GD. Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine. J Control Release. 2011;155:193-9.
3. Xu X, Jha AK, Harrington DA, Farach-Carson MC, Jia X. Hyaluronic Acid-Based Hydrogels: from a Natural Polysaccharide to Complex Networks. Soft Matter. 2012;8:3280-3294.
4. Xian Xu, Amit K. Jha, Daniel A. Harrington, Mary C. Farach-Carson,' Xinqiao Jia, Hyaluronic Acid-Based Hydrogels: from a Natural Polysaccharide to Complex Networks. Soft Matter. 2012; 8: 3280–3294.
5. Tezel A, Fredrickson GH. The science of hyaluronic acid dermal fillers. J Cos & Laser Ther. 2008;10:35-42.
6. Wang F, Garza LA, Kang S, Varani J, Orringer JS, Fisher GJ, Voorhees JJ. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. Arch Dermatol 2007:143:155-63
7. Webber J, Jenkins RH, Meran S, Phillips A, Steadman R. Modulation of TGFbeta1-dependent myofibroblast differentiation by hyaluronan. Am J Pathol. 2009 Jul;175:148-60.
8. Kastner S, Thomas GJ, Jenkins RH, Davies M, Steadman Hyaluronan induces the selective accumulation of matrix- and cell-associated proteoglycans by mesenchymal cells. Am J Pathol. 2007;171;1811-21.
9. Meran S, Luo DD, Simpson R, Martin J, Wells A, Steadman R, Phillips AO. Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interaction. J Biol Chem. 2011;286:17618-30.
10. Simpson RM, Meran S, Thomas D, Stephens P, Bowen T, Steadman R, Philips A. Age-related changers in pericellular hyaluron organization leads to impaired dermal fibroblast to myofibroblast differentiation. Am J Pathol 175:1915-28.

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