14, 22, and 30, respectively, suggesting a therapeutic effect
sustained beyond the treatment period. Approximately one
third of patients remained clear at week 22. At week 30, the
treatment arm with coal tar and UVB novel medical device’s
TPA score (2.8) was superior to the control’s TPA score (5.1).
No significant adverse events were reported, and the most
common adverse event was folliculitis.
DISCUSSION
Although Goeckerman therapy has been well studied as an
effective therapy for psoriasis, it is not widely used given the
travel required, time consuming regimen, and specialized
services needed. Here we report a significant reduction in
plaque severity as well as a sustained response after a
home-based treatment utilizing the two main components of the
Goeckerman regimen.
DISCLOSURES
Dr. Jeffrey Sugarman and Evan Anderson own shares of Luma Therapeutics, the company that developed the technology.
Funding: This study was sponsored by Luma Therapeutics Trial registered on clintrials.gov: NCT03180866
Funding: This study was sponsored by Luma Therapeutics Trial registered on clintrials.gov: NCT03180866
ACKNOWLEDGMENTS
Dr. Jeffrey Sugarman, Principal Investigator, had full access to
all the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
REFERENCES
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2. Foerster J, Dawe R. Phototherapy achieves significant cost savings by the delay of drug-based treatment in psoriasis. Photderm Photoimm Photomed. 2020;36(2):90-96. doi:10.1111/phpp.12511
3. Yu Z, Huang KP, Buzney EA. Creating and Managing a Phototherapy Center. Dermatol Clin. 2020;38(1):137-143.doi:10.1016/j.det.2019.08.014
2. Foerster J, Dawe R. Phototherapy achieves significant cost savings by the delay of drug-based treatment in psoriasis. Photderm Photoimm Photomed. 2020;36(2):90-96. doi:10.1111/phpp.12511
3. Yu Z, Huang KP, Buzney EA. Creating and Managing a Phototherapy Center. Dermatol Clin. 2020;38(1):137-143.doi:10.1016/j.det.2019.08.014
AUTHOR CORRESPONDENCE
Nicholas D. Brownstone MD Nicholas.Brownstone@ucsf.edu