with topical tacrolimus, pimecrolimus,3 and imiquimod,4 as well
as surgical treatment with either CO2
5 or ablative erbium:YAG6
lasers, although in some cases the disease recurred (CO2 laser)
or was not cleared histologically (imiquimod). Furthermore,
Zoon’s balanitis has also been reported to precede squamous
cell carcinoma7 and squamous cell carcinoma in situ.8 Given this
information, it may be appropriate to consider either medical
treatment of this condition or minimally invasive surgical procedures
such as lasers before surgical circumcision. Furthermore,
consideration should be taken to follow these patients for development
of malignancy.
DISCLOSURES
None of the authors have declared any relevant conflicts.
REFERENCES
- Bolognia JL, Jorizzo JL, Schaffer JV, et al. Dermatology, 3rd ed. Spain: Elsevier, 2012.
- Toker SC, Baskan EB, Tunali S, et al. Zoon's balanitis in a circumcised man.J Am Acad Dermatol. 2007; 57(2 Suppl):S6-7.
- Delgado L, Brandt HR, Ortolan DG, et al. Zoon's plasma cell balanitis: a report of two cases treated with pimecrolimus. An Bras Dermatol. 2011; 86(4 Suppl 1):S35-8.
- Marconi B, Campanati A, Simonetti O, et al. Zoon's balanitis treated with imiquimod 5% cream. Eur J Dermatol. 2010; 20(1):134-5.
- Retamar RA, Kien MC, Chouela EN. Zoon's balanitis: presentation of 15 patients, five treated with a carbon dioxide laser. Int J Dermatol. 2003; 42(4):305-7.
- Wollina U. Ablative erbium:YAG laser treatment of idiopathic chronic inflammatory non-cicatricial balanoposthitis (Zoon's disease)--a series of 20 patients with long-term outcome. J Cosmet Laser Ther. 2010; 12(3):120-3.
- Balato N, Scalvenzi M, La Bella S, et al. Zoon's Balanitis: Benign or Premalignant Lesion? Case Rep Dermatol. 2009; 1(1):7-10.
- Starritt E, Lee S. Erythroplasia of Queyrat of the glans penis on a background of Zoon's plasma cell balanitis. Australas J Dermatol. 2008; 49(2):103-5.
AUTHOR CORRESPONDENCE
Joseph C. Pierson MDjoseph.pierson@uvm.edu