Resident Rounds Part III. Case Report: Genital Ulcers

October 2014 | Volume 13 | Issue 10 | Features | 1290 | Copyright © October 2014


Jeremy M. Hugh MD, Kendra Lesiak MD, Laura A. Greene MD, and Joseph C. Pierson MD

University of Vermont College of Medicine, Burlington, VT

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with topical tacrolimus, pimecrolimus,3 and imiquimod,4 as well as surgical treatment with either CO2 5 or ablative erbium:YAG6 lasers, although in some cases the disease recurred (CO2 laser) or was not cleared histologically (imiquimod). Furthermore, Zoon’s balanitis has also been reported to precede squamous cell carcinoma7 and squamous cell carcinoma in situ.8 Given this information, it may be appropriate to consider either medical treatment of this condition or minimally invasive surgical procedures such as lasers before surgical circumcision. Furthermore, consideration should be taken to follow these patients for development of malignancy.

DISCLOSURES

None of the authors have declared any relevant conflicts.

REFERENCES

  1. Bolognia JL, Jorizzo JL, Schaffer JV, et al. Dermatology, 3rd ed. Spain: Elsevier, 2012.
  2. Toker SC, Baskan EB, Tunali S, et al. Zoon's balanitis in a circumcised man.J Am Acad Dermatol. 2007; 57(2 Suppl):S6-7.
  3. Delgado L, Brandt HR, Ortolan DG, et al. Zoon's plasma cell balanitis: a report of two cases treated with pimecrolimus. An Bras Dermatol. 2011; 86(4 Suppl 1):S35-8.
  4. Marconi B, Campanati A, Simonetti O, et al. Zoon's balanitis treated with imiquimod 5% cream. Eur J Dermatol. 2010; 20(1):134-5.
  5. Retamar RA, Kien MC, Chouela EN. Zoon's balanitis: presentation of 15 patients, five treated with a carbon dioxide laser. Int J Dermatol. 2003; 42(4):305-7.
  6. Wollina U. Ablative erbium:YAG laser treatment of idiopathic chronic inflammatory non-cicatricial balanoposthitis (Zoon's disease)--a series of 20 patients with long-term outcome. J Cosmet Laser Ther. 2010; 12(3):120-3.
  7. Balato N, Scalvenzi M, La Bella S, et al. Zoon's Balanitis: Benign or Premalignant Lesion? Case Rep Dermatol. 2009; 1(1):7-10.
  8. Starritt E, Lee S. Erythroplasia of Queyrat of the glans penis on a background of Zoon's plasma cell balanitis. Australas J Dermatol. 2008; 49(2):103-5.

AUTHOR CORRESPONDENCE

Joseph C. Pierson MDjoseph.pierson@uvm.edu