Pipeline Previews

October 2014 | Volume 13 | Issue 10 | Features | 1293 | Copyright © October 2014


ACTICLATE™ should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. Tablets are contraindicated in persons who have shown hypersensitivity to any of the tetracyclines.

Azelaic Acid 15% Foam a Possible Treatment for Papulopustular Rosacea

Bayer HealthCare announced positive results from a Phase III trial that evaluated a 15% foam formulation of its compound azelaic acid (AzA) for the topical treatment of inflammatory papules and pustules of rosacea. An AzA foam formulation is a potential treatment option to complement the currently available AzA gel formulation. Papulopustular rosacea is a skin disease causing inflammatory lesions (papules and pustules) as well as erythema (redness) on the nose, cheeks, chin and forehead.
After evaluating safety and tolerability, the overall frequency of adverse events (AEs) was 31% in the AzA 15% foam group and 25% in the vehicle group. The vast majority of AEs in both groups were mild to moderate. In the AzA 15% foam group, no severe drug-related and no serious drug-related AEs were reported. Overall, less than 2% of subjects discontinued treatment due to an AE, the frequency being slightly lower in the AzA 15% foam group. Detailed results of the trial will be presented at upcoming scientific meetings.

Exuviance Super Retinol Concentrate Unveiled

NeoStrata Company, Inc., the creator of the original Glycolic Acid peel, enthusiastically unveils the next major innovation in antiaging skincare– Exuviance Super Retinol Concentrate. The unique breakthrough formula goes beyond diminishing wrinkles, specifically created to defy gravity for superior, visible lifting and firming results.
The brand's patented NeoGlucosamine® is clinically proven to work synergistically with Retinol, super-charging and intensifying the ingredient's volumizing effects versus Retinol alone to lift and firm skin. A time-released microencapsulation delivers pure Retinol, maximizing potency and benefits, while minimizing irritation potential.
The high-performance ingredients in this formulation help build natural collagen and its surrounding support matrix to lift, firm and smooth wrinkles from the inside out while also increasing cellular renewal, refining texture and diminishing the appearance of age spots.