Pharmacokinetic Profile, Safety, and Tolerability of Topical Berdazimer Gel, 10.3% in Patients With Molluscum Contagiosum

October 2022 | Volume 21 | Issue 10 | 1104 | Copyright © October 2022


Published online September 26, 2022

Martina Cartwright PhDa, Carolyn Enloe MPHa, Stephen Stripling MDb, Tomoko Maeda-Chubachi MD PhD MBAa

aMedical Affairs, Novan, Inc., Durham, NC
bPediatric Department, Coastal Pediatric Research, Charleston, SC



included in the PK, safety, and ITT populations. The mean age of patients was 5.3 years (range, 2-12), half were females, and most were white (33/34 [97.1%]) and non-Hispanic/Latino (29/34 [85.3%]) (Table 1). The mean number of MC lesions at baseline was 50.2 (median, 35.0; range, 21-212).

Treatment Compliance
During the PK period, patients/caregivers were highly (97.7%) compliant with treatment application.

Pharmacokinetic Parameters
No patients had quantifiable plasma hMPA3 concentrations at any timepoint on day 1, and 2 patients had quantifiable