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Dec 10
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Pharmacokinetic Comparison of Once-Daily Topical Minocycline Foam 4% vs Oral Minocycline for Moderate-to-Severe Acne

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INTRODUCTIONAcne vulgaris (AV) is one of the most common skin diseases, affecting 40 to 50 million persons of all ages and races in the United States.1 Most teenagers—approximately 85%—will have…
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Dec 10
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Improvement of Actinic Keratoses Using Topical DNA Repair Enzymes: A Randomized Placebo-Controlled Trial

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INTRODUCTIONActinic keratoses (AKs) are common, early-stage proliferations of abnormal keratinocytes, which may progress into NMSCs, particularly squamous cell carcinomas (SCC). SCC is the second leading cause of skin cancer deaths…
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Dec 10
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Serpiginous Purpuric Eruption of the Leg

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CASE REPORTDISCUSSIONThe histopathological findings of Wells’ Syndrome include dermal edema and eosinophilic infiltration. ‘Flame figures’ are also present, formed by eosinophilic granules coating collagen bundles.3 Of note, ‘flame figures’ are…
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Dec 10
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Autoimmune Progesterone Dermatitis: A Diagnosis to Consider in a Patient With Cyclical Cutaneous Eruptions

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CASE REPORTThe patient is a 32-year-old woman (gravida 2, para 2) who presented with approximately a 3-year history of a recurrent eruption on her face and left arm. The eruption…
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Dec 10
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Trimethoprim-Sulfamethoxazole-Induced Drug Eruption With Eosinophilia and Systemic Symptoms (DRESS)

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INTRODUCTIONDrug rash with eosinophilia and systemic symptoms (DRESS) is a severe and potentially life threatening adverse drug reaction. First reported in 1937 as an “exfoliative dermatitis following the administration of…
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Dec 10
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Development of Halo Nevi in a Lung Cancer Patient: A Novel Immune-Related Cutaneous Event from Atezolizumab

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INTRODUCTIONCytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death-1 (PD-1) are immune checkpoint molecules that are vital components of a healthy immune system. When activated, the CTLA-4 and PD-1 pathways…
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Dec 10
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Granuloma Annulare Secondary to Vemurafenib Therapy for Lung Adenocarcinoma

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INTRODUCTIONGranuloma annulare (GA) refers to eruptions of benign pink or flesh-colored papules that classically form ring-shaped groupings. These lesions are typically asymptomatic and self-limited. GA occurs most often in patients…
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Dec 10
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Managing Seborrheic Keratoses: Evolving Strategies for Optimizing Patient Outcomes

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INTRODUCTIONThe seborrheic keratosis (SK) is the most common benign skin tumor of middle-aged and elderly adults. It affects roughly 83 million Americans, with an average of 155 new cases of…
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Dec 10
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The Alexiades Filler Lift Method

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In this article, I present my unique method of injecting dermal fillers in the hairline to create a lifting effect that is concealed from view and does not distort the…
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Dec 10
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Treatment of Photoaging With a Dual-Wavelength, 532 nm and 1,064 nm Picosecond-Domain Laser Producing a Fractionated Treatment Beam Using a Holographic Optic

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INTRODUCTIONMost of the signs we associate with skin aging including: fine lines and wrinkles, enlarged pores, pigmentary alterations, skin sagging, and redness, are due to long-term sun-exposure and not chronological…
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Dec 10
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In-Vivo Histological Analysis of a Fractional CO2 Laser System Intended for Treatment of Soft Tissue

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INTRODUCTIONAging skin can be in part characterized by the appearance of fine lines and wrinkles, as well as an overall decline in skin texture and tone.1 Skin resurfacing refers to…
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Dec 10
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Lasers, Light, and the Treatment of Acne: A Comprehensive Review of the Literature

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INTRODUCTIONAcne vulgaris is a common dermatologic condition affecting individuals of both genders and all skin types with an estimated prevalence of 70 to 87%.1-2 It typically begins in adolescence and…
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