INTRODUCTIONPsoriasisPsoriasis is a chronic, immune-mediated, inflammatory disease that affects the skin (including the scalp, hands, and feet) and the nails. It affects between 1.5–5% of the population in developed countries,1…
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INTRODUCTIONTreatment of moderate to severe plaque psoriasis has improved substantially with the introduction of treatments that have demonstrated the ability to reduce disease severity and improve quality of life (QOL).1,2…
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INTRODUCTIONGranular parakeratosis is a rare disorder of keratinization with a distinctive histology wherein parakeratosis with retention of keratohyaline granules is noted in the epidermis. It was first described in 1991…
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Twenty-Nail Transverse Melanonychia Induced by Hydroxyurea: Case Report and Review of the Literature
CASE REPORTA 51-year-old African American female with a history of sickle cell disease, hypertension, and chronic kidney disease presented to our dermatology clinic with discoloration of her fingernails and toenails.…
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INTRODUCTIONCASE REPORTDISCUSSIONfatigue, nausea, chills, diarrhea, and rash (not specifically defined in the studies),5-7 but no reports of herpes zoster were found.PDT is proven to be a highly efficacious treatment for…
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As clinicians, we tend to eagerly await new drug approvals, especially when the drug represents a new class of treatment and is likely to fulfill an unmet need. We analyze…
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INTRODUCTIONPsoriasis is a chronic, immune-mediated, inflammatory skin disease characterized by erythematous and scaly plaques. The prevalence of psoriasis varies across the globe, with estimates ranging from 0.09% to 5.1% depending…
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INTRODUCTIONPsoriatic arthritis (PsA) is an immune-mediated, inflammatory disease of the peripheral joints, axial spine, and entheses. The frequency of PsA among patients with psoriasis has been estimated at up to…
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INTRODUCTIONPrevious studies indicate that human skin is a target for infrared A radiation (IRA).1 Infrared A (IRA) irradiation leads to increased expression of matrix metalloproteinase 1 (MMP1), an enzyme involved…
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INTRODUCTIONBetween 80% and 100% of individuals over the age of 50 have at least one seborrheic keratosis (SK). These lesions may be of concern to the patient by either being…
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