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Dec 10
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A Phase 2, Multicenter, Double-Blind, Randomized, Vehicle Controlled Clinical Study to Assess the Safety and Efficacy of a Halobetasol/Tazarotene Fixed Combination in the Treatment of Plaque Psoriasis

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INTRODUCTIONPsoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression and affects approximately 2% of the population.1-3 Treatment options focus on relieving symptoms, reducing in ammation, induration,…
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Dec 10
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Topical Approaches to Improve Surgical Outcomes and Wound Healing: A Review of Efficacy and Safety

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DISCUSSIONSurgical procedures are an essential piece of a dermatologist’s practice. In fact, it has been reported that dermatologists perform over 25 million minor surgical procedures annually.1,2 A major focus of…
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Dec 10
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Use of Biologics in Private Practice: Nine Years of Lessons and Learning

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INRODUCTIONPsoriasis is one of the common conditions seen by dermatologists. The worldwide prevalence is described at 2%. One-third of the patients have severe involvement and 5-30% are affected by psoriatic…
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Dec 10
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Patient Preference for Dosing Frequency Based on Prior Biologic Experience

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INTRODUCTIONThe advent of biologics has improved quality of life, clinical outcomes, and productivity among patients treated for psoriasis.1,2 Furthermore, several studies have found greater adherence to biologic treatments compared to…
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Dec 10
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Dermatologists: Collaborating With Payers to Optimize Coverage Policies

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INTRODUCTIONDermatologists are often frustrated by payer constraints that limit their ability to optimize patient treatment. Matters are increasingly contentious between payers and physicians in this age when biologics offer patients…
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Dec 10
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Two Multicenter, Randomized, Double-Blind, Parallel Group Comparison Studies of a Novel Enhanced Lotion Formulation of Halobetasol Propionate, 0.05% Versus Its Vehicle in Adult Subjects With Plaque Psoriasis

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INTRODUCTIONPsoriasis, a chronic autoimmune disease manifested as inflammatory dermatosis, affects 1-3% of the United States population and 0.5-4.6% of the worldwide population.1 Plaque psoriasis, the most common form of the disease,…
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Dec 10
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Anti-Pruritic Efficacy of Itch Relief Lotion and Cream in Patients With Atopic History: Comparison With Hydrocortisone Cream

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INTRODUCTIONAtopic dermatitis (AD) is an inflammatory skin disease characterized by intense itching and recurrent eczematous lesions and associated with sleep disturbance, psychological symptoms, and impaired quality of life.1-8 It may…
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Dec 10
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Treatment of Atopic Dermatitis in the United States: Analysis of Data from the National Ambulatory Medical Care Survey

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INTRODUCTIONAtopic dermatitis (AD) is a common inflammatory disease of the skin that affects both adult and pediatric patients. While it primarily begins in childhood, AD persists into adulthood more than…
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Dec 10
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Expert Consensus on Cosmetic Outcomes After Treatment of Actinic Keratosis

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INTRODUCTIONActinic keratosis (AK) is a marker for photodamaged skin.1 Dermatologists treat AKs primarily because these lesions have the potential to progress to invasive squamous cell carcinoma (SCC). Most patients seek…
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Dec 10
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Subungual Melanoma In Situ Treated With Imiquimod 5% Cream After Conservative Surgery Recurrence

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INTRODUCTIONSubungual melanoma (SUM) is an uncommon form of acrolentiginous melanoma that represents about 0.7 to 3.5 percent of all subtypes of melanoma.1,2 Amputation was long thought to be the best…
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Dec 10
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Photodynamic Therapy Effectively Treats Actinic Keratoses Without Pre-Illumination Incubation Time

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INTRODUCTIONActinic keratoses (AKs) are dysplastic premalignant lesions of the epidermis that often occur in Fitzpatrick I-III skin-type patients who have been chronically exposed to sunlight. If left untreated, AKs can…
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Dec 10
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Successful Treatment of Generalized Essential Telangiectasia With 6-Mercaptopurine

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INTRODUCTIONGeneralized essential telangiectasia (GET) is a rare disease characterized by widespread telangiectasias of the lower limbs that may spread superiorly to involve other parts of the body.1,2 GET is typically…
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