Percutaneous AbsorptionTraditional VehiclesOintmentsCreams SolutionsSolutionsGelsFoamsEmerging Carrier Platforms for Topical Drug DeliveryLiposomesconfers liposomes amphipathic properties, enabling encapsulation of hydrophilic and hydrophobic drugs.23 Liposomal carriers increase drug stability, enhance their therapeutic effects, and…

Oral and topical retinoids are widely used for treating Mycosis Fungoides (MF), the most common form of cutaneous t-cell lymphoma (CTCL).1,2 While the retinoid- X-receptor-selective bexarotene is the only topical…

INTRODUCTIONIn this report, we summarize data captured from the on-going PSOLAR registry from June 20, 2007 (registry launch) to August 23, 2013 (the most recent data extract). Patients are grouped…

INTRODUCTION The struggle to reduce the buildup of undesired adipose tissue in the human body is a century old.1 After the revolution brought about by Klein´s liposuction innovations during the…

introductionSelection of PrototypesPrototype Evaluation CriteriaIn-Vitro Nail PenetrationIn-Vivo EfficacyFinal Formulation Selection and EvaluationIn-Vitro Nail PenetrationNail Penetration in Onychomycosis PatientsSpreading to the Site of InfectionCommentACKNOWLEDGMENTDISCLOSUREsReferences Scher RK, Coppa LM. Advances in the…

INTRODUCTION The ability to visualize what is invisible to the naked eye is critical in medicine. Robert Hooke invented the first simple microscope in the 1660s and used it to…

INTRODUCTIONMATERIALS AND METHODSPercutaneous AbsorptionBiopsies and BiomarkersBio-InstrumentationSubjects and Clinical AssessmentRESULTSPercutaneous AbsorptionBiopsy AnalysisUltrasound AnalysisClinical AssessmentsSelf-AssessmentDISCUSSIONDISCLOSUREsReferences Gilchrest BA. Skin aging and photoaging: An overview. J Am Acad Dermatol. 1989:21;610-613 Dzubow L. The aging…

INTRODUCTION Dermatofibrosarcoma protuberans (DFSP) is rare tumor. DFSP only represents 1-2% of all soft tissue sarcomas.1 The overall incidence of DFSP ranges from 0.8 per million to 5 per million.…

INTRODUCTIONIt is now well recognized that the epidermal barrier serves not only to prevent the entry of exogenous factors such as irritants or allergens, but also to mediate disease. Although…

INTRODUCTION A burgeoning non-invasive treatment for skin laxity is transcutaneous thermogenesis – achieved using ultrasound, radiofrequency, or light. These approaches use heat to promote neocollagenesis, denaturation of collagen cross-links, activation…

INTRODUCTIONMycobacterium avium intracellulare complex (MAC) includes 2 genetically similar organisms: Mycobacterium avium and Mycobacterium intracellulare. MAC species are widely found in the environment, and are a major cause of nontuberculous…

INTRODUCTION The prevalence of non tuburculous mycobacterial cutaneous infections is small, with an estimated rate of between 0.9 cases per 100,000.1 Many dermatologists will not see a case of cutaneous…